Identification of human hornerin and its expression in regenerating and psoriatic skin.

TL;DR: It is concluded that IL‐17A downregulates the expression of filaggrin and genes important for cellular adhesion which could affect epidermal barrier formation.

TL;DR: The results show that the changes accompanying the transition from non-lesional to acute to chronic inflammation in AD are quantitative rather than qualitative, with chronic AD having heightened Th2, Th1, Th17, and IL36 responses and skin barrier repair mechanisms.

TL;DR: In this overview, the complete life of keratinocytes is described, from the proliferative organization to the process of desquamation.

TL;DR: Immunoelectron microscopy demonstrated that PAD1 and PAD3 are co-located with filaggrin within the filamentous matrix of the deeper corneocytes where the protein is deiminated, which strongly suggests that both isoforms are involved in the deimination of filag Grin.

TL;DR: This paper will review some important aspects of the biology of epidermal differentiation and the recent advances in understanding of the molecular mechanism underlying genetic diseases of keratinization.

TL;DR: According to Alibert, congenital ichthyosis often appears to be hereditary; at other times it seems to depend on some strong mental impression received by the mother as discussed by the authors.

TL;DR: It is concluded that the repetin gene represents a novel member of the "fused gene" subgroup of the S100 gene family encoding multifunctional epidermal matrix proteins.

TL;DR: It is proposed that the distribution of envoplakin at the interdesmosomal plasma membrane depends on heterodimerization with periplakin and that the NH2 terminus of periplkin therefore plays a key role in forming the scaffold on which the cornified envelope is assembled.