Human Protein Reference Database

TL;DR: This study validates the "breast tumor intrinsic" subtype classification as an objective means of tumor classification that should be translated into a clinical assay for further retrospective and prospective validation.

TL;DR: This chapter reveals the protocol and key insights into the isolation, purification and characterization of exosomes, distinct from shed microvesicles and apoptotic blebs, and concludes that density-based separation (DG-Exos) provides significant advantages for exosome isolation when the use of immunoaffinity capture is limited.

TL;DR: There is an increasing number of noteworthy methods for predicting protein function from sequence and structural data alone, many of which are readily available to cell biologists who are aware of the strengths and pitfalls of each available technique.

TL;DR: The functionality of the ConsensusPathDB web interface is described, where users can search and visualize interaction networks, upload, modify and expand networks in BioPAX, SBML or PSI-MI format, or carry out over-representation analysis with uploaded identifier lists with respect to substructures derived from the integrated interaction network.