Journal Article10.1080/00016489.2020.1821246
Histopathology of laryngomalacia.
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TL;DR: The histology reports of 61 aryepiglottoplasty specimens resected between 1 October 2014 and 31 October 2018 suggest a mild concurrent laryngitis/supraglottitis in most cases and supports the theory of chondropathic aetiology.
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Abstract: Laryngomalacia is the commonest laryngeal anomaly and cause of stridor in children. Although most cases are self-limiting, failure to thrive, hypoxaemia or significant apnoeic episodes may warrant ...
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Citations
Laryngomalacia and Obstructive Sleep Apnea in Children: From Diagnosis to Treatment
Luca Cerritelli,Andrea Migliorelli,Alessio Larini,Andrea Catalano,Alberto Caranti,Chiara Bianchini,Andrea Ciorba,Francesco Stomeo,Claudio Vicini,Stefano Pelucchi +9 more
TL;DR: This review examines the association between laryngomalacia and obstructive sleep apnea in children, discussing epidemiology, diagnostic tools, and treatments, including medical and surgical options such as supraglottoplasty, to address this common condition.
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Neuropathological features of pediatric laryngomalacia
Inbal Hazkani,Matthew Schniederjan,Ching Siong Tey,Anthony Botros,Kristan P. Alfonso +4 more
TL;DR: Histopathology of submucosal nerves in laryngomalacia shows nerve hypertrophy.
References
Laryngomalacia. The search for the second lesion.
TL;DR: To determine the necessity of rigid endoscopy in the diagnosis and management of laryngomalacia and its associated synchronous airway lesions (SALs) and to determine the need for epiglottoplasty, a retrospective medical chart review was conducted.
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Aryepiglottoplasty for laryngomalacia: 100 consecutive cases.
TL;DR: Endoscopic aryepiglottoplasty remains the operation of choice for patients with severe laryngomalacia, however, in the presence of neurological disease surgery is less likely to be successful.
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Histological insight into the pathogenesis of severe laryngomalacia
TL;DR: The histopathology of tissue excised during the treatment of severe laryngomalacia was dominated by submucosal edema and lymphatic dilation, and intraepithelial inflammation was rare to absent in all sections.
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Systematic review of endoscopic airway findings in children with gastroesophageal reflux disease.
Jason G. May,Priyanka Shah,Lori A. Lemonnier,Gaurav Bhatti,Jovana Koscica,James M. Coticchia +5 more
TL;DR: Certain findings commonly encountered on endoscopic evaluation of the larynx and trachea in children who present with respiratory symptoms do indeed demonstrate a correlation with the presence of laryngopharyngeal reflux disease and may indicate the need for antireflux therapy.
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Synchronous airway lesions and associated anomalies in children with laryngomalacia evaluated with rigid endoscopy
TL;DR: Despite having indications for rigid endoscopy, many children with laryngomalacia do not have SALs, which even when present, are rarely clinically significant, and the presence of SALs did not affect the length of hospital stay or the time to resolution of symptoms.
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