Journal Article10.1021/JA00225A063
Highly efficient, practical approach to natural taxol
Jean Noel Denis,Andrew E. Greene,Daniel Guenard,Francoise Gueritte-Voegelein,Lydie. Mangatal,Pierre Potier +5 more
658
About: This article is published in Journal of the American Chemical Society. The article was published on 01 Aug 1988.
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Citations
Screening for pharmaceutically important taxoids in Taxus baccata var. Aurea corr. with CC/SPE/HPLC-PDA procedure.
TL;DR: The applied method enabled determination of four taxoids commonly occurring in yew extracts and the largest amounts isolated were of 10-deacetylbaccatin III, then 10- deacetylpaclitaxel and 7-xyloside-10-deacetyltaxol C, all compounds considered to be pac litaxel precursors in semisynthesis.
From taxol to taxol®: The changing identities and ownership of an anti-cancer drug
Vivien Walsh,Jordan Goodman +1 more
TL;DR: The emergence and evolution of taxol is analyzed, which explores its role in several controversies: the destruction of old-growth forests, public participation in policy making, and the privatization of intellectual property and its effect on the price of drugs.
Recent advances in the chemistry of taxol.
TL;DR: The history of the development of the important anticancer drug taxol is briefly described in this paper, and recent studies of its chemistry and tubulin-binding conformation are then presented.
El romerillo (Taxus globosa Schlecht.): Biología, dificultades y perspectivas de su uso
F Zavala Chávez,M Soto Hernández,María Teresa Rodríguez González +2 more
- 01 Jun 2001
TL;DR: A review of literature, laboratory and field work, and herbarium study on taxus is presented in this paper, where the authors present integrated information on Taxus, particularly the Mexican species T. globosa, and conclude that its potential for use and the need to investigate it in order to protect, propagate, conserve, and possibly cultivate it.
An Overview on Taxol Production Technology and Its Applications as Anticancer Agent
Apara Sharma,Shashi Kant Bhatia,Aditya Banyal,Ishita Chanana,Anil Kumar,Duni Chand,Saurabh Kulshrestha,Pradeep Kumar +7 more
TL;DR: The aim of this review article is to cover everything from the discovery of taxol through the development of new natural resource-based biotechnology techniques, as well as pointing to some future opportunities.