Journal Article10.1088/1361-6528/AC31E5
High antioxidant activity of gadolinium-yttrium orthovanadate nanoparticles in cell-free and biological milieu.
Pavel Maksimchuk,K.O. Hubenko,V. V. Seminko,V L Karbivskii,Anton Tkachenko,Anatolii Onishchenko,V Yu Prokopyuk,V Yu Prokopyuk,S. L. Yefimova +8 more
TL;DR: In this paper, the authors reported on high antioxidant behavior (enzyme-like activity) of GdYVO4:Eu3+nanoparticles revealed by spectroscopic methods both in cell free and biological milieu using various ROS sensors.
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Abstract: Oxidative stress caused by an overproduction of reactive oxygen species (ROS) is the key factor in developing a variety of pathological conditions. Recently various nanomaterials have attracted growing interest as nanoantioxidants with ROS-regulating ability. Here, for the first time, we report on high antioxidant behavior (enzyme-like activity) of GdYVO4:Eu3+nanoparticles (GdYVO NPs) revealed by spectroscopic methods both in cell-free and biological milieu using various ROS sensors. It was revealed that GdYVO NPs (d= 2 nm) effectively scavenge hydroxyl radicals·OH,superoxide anionsO2·-,hydrogen peroxideH2O2,peroxyl radicalsROO·,and remarkably reduce the lipopolysaccharide-induced ROS generation in rat leukocytes. The antioxidant activity of GdYVO NPs is ascribed to high amount of V4+and V3+ions in the structure of the NPs and the reversible switchingV3+↔V4+andV4+↔V5+vanadium oxidation states.
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Citations
Green synthesis of CeVO_4 nanoparticles using Azadirechta indica leaves extract and their promising applications as an antioxidant and anticancer agent
Suresh Ghotekar,Parita Basnet,Kun-Yi Andrew Lin,Abbas Rahdar,Alejandro Pérez-Larios,Vimala S. Gandhi,Rajeshwari Oza +6 more
TL;DR: Results indicated that the as-synthesized CeVO_4 nanoparticles evinced a pseudo-spherical shape with a size of 43 nm, and as-prepared NPs were subjected to anticancer performance against HeLa cancer cell lines and antioxidant efficacy using DPPH and ABTS assays.
13
Platinum nanoflowers stabilized with aloe polysaccharides for detection of organophosphorus pesticides in food.
Huan Zhao,Ruyu Li,Tingting Zhang,Lijie Zhou,Longgang Wang,Zengsheng Han,Sihang Liu,Jin Zhang +7 more
TL;DR: This work extracted aloe polysaccharide from aloe vera with the number average molecular weight of 29,271 Da and investigated its reducing property, and developed a simple and effective strategy for the sensitive colorimetric detection of organophosphorus pesticides in food using biocompatible AP-Ptn NFs.
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Platinum Palladium Bimetallic Nanozymes Stabilized with Vancomycin for the Sensitive Colorimetric Determination of L-cysteine
Huan Zhao,Kai Liu,Lijie Zhou,Tingting Zhang,Zengsheng Han,Longgang Wang,Xianbing Ji,Yan-lin Cui,Jie Hu,Guanglong Ma +9 more
TL;DR: This work synthesized platinum palladium bimetallic nanoparticles (Van-Ptm/Pdn NPs) using vancomycin hydrochloride (Van) as a stabilizer, which exhibited high oxidase-like catalytic activity and developed a simple and effective strategy for the sensitive colorimetric detection of L-cysteine using biocompatible Van-Pt1/Pd1 NPs.
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The state of metabolic parameters of the blood in white rats under conditions of long-term oral administration of gadolinium orthovanadate nanoparticles under food stress
A. V. Masliuk,O.L. Orobchenko,Matthew Romanko,Yu. Koreneva,V K Klochkov,Svetlana L. Yefimova,Nataliya S. Kavok +6 more
TL;DR: In this paper , the metabolic parameters of the blood in rats under long-term oral administration of nanoparticles of one of the representatives of rare earth elements (NP GdVO4:Eu3+) under food stress were studied.
2
Assessment of anti-inflammatory properties of metal nanoparticles as potential means for the correction of pathologies on the reproductive system in animals
V I Koshevoy,S. V. Naumenko,V. R. Serhienko +2 more
- 27 Sep 2023
TL;DR: The article summarizes information from modern scientific sources regarding the development of drugs with pronounced anti-inflammatory properties based on nanoparticles (NPs) of metals, in particular noble ones – Silver and Gold, which exhibit antimicrobial and antioxidant effects and contribute to the reduction of inflammatory processes in various pathological conditions, which is the scientific basis for their introduction into the practice of reproductive veterinary medicine.
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