Her-2/neu overexpression is associated with thrombospondin-1-related angiogenesis and thrombospondin-1-unrelated lymphangiogenesis in breast cancer
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TL;DR: In vivo results showed that Her-2/ neu affects the biological manifestations of breast cancer by increasing angiogenesis and lymphangiogenesis, which is TSP-1-unrelated.
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About: This article is published in Gynecology and Minimally Invasive Therapy. The article was published on 01 Nov 2013. and is currently open access. The article focuses on the topics: Trastuzumab & Lymphangiogenesis.
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Citations
Angiogenesis: Managing the Culprits behind Tumorigenesis and Metastasis
Ashwaq Hamid Salem Yehya,Muhammad Asif,Sven H. Petersen,Ayappa V. Subramaniam,Koji Kono,Amin Malik Shah Abdul Majid,Chern Ein Oon +6 more
TL;DR: A complimentary combination of different agents that target multiple molecules in the angiogenic cascade may optimize inhibition of angiogenesis and improve clinical benefit in the cancer patients.
•Dissertation
Expresión de TSP-1 en carcinoma de mama
García Salguero,Ana Isabel +1 more
- 01 Jan 2016
TL;DR: This estudio se intenta averiguar el papel de TSP-1 en el carcinoma de mama mediante la valoracion de the expresion inmunohistoquimica de la misma en el estroma y en las celulas tumorales, usando la tecnica de tissue microarrays (TMA).
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TL;DR: The addition of trastuzumab to chemotherapy was associated with a longer time to disease progression, a higher rate of objective response, a longer duration of response, and a lower rate of death at 1 year.
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