Journal Article10.1016/J.JHEP.2009.01.019
Hepatitis C virus genotype 1b as a risk factor for hepatocellular carcinoma development: A meta-analysis
TL;DR: This meta-analysis suggests that HCV genotype 1b plays an important role in HCC development, especially in patients with early stage liver disease.
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About: This article is published in Journal of Hepatology. The article was published on 01 Jun 2009. The article focuses on the topics: Risk factor & Hepatitis C.
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Citations
EASL-EORTC clinical practice guidelines : management of hepatocellular carcinoma
Peter R. Galle,Alejandro Forner,Josep M. Llovet,Vincenzo Mazzaferro,Fabio Piscaglia,Jean-Luc Raoul,Peter Schirmacher,Valérie Vilgrain +7 more
TL;DR: The following Clinical Practice Guidelines will give up-to-date advice for the clinical management of patients with hepatocellular carcinoma, as well as providing an in-depth review of all the relevant data leading to the conclusions herein.
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TL;DR: The purpose of this document is to assist physicians, patients, health-care providers, and health-policy makers from Europe and worldwide in the decision-making process according to evidencebased data.
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Epidemiology of hepatocellular carcinoma: consider the population.
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TL;DR: This review discusses the latest trends of HCC globally and in the United States and provides an evidence-based commentary on the risk factors and lists some of the preventive measures to reduce the incidence.
References
Lack of correlation between hepatitis C virus genotypes and clinical course of hepatitis C virus-related cirrhosis
TL;DR: It is indicated that HCV‐genotypes do not have a significant effect on the severity and outcome of liver disease in patients with chronic HCVs and patients infected by more than one genotype showed the most unfavorable course of disease.
Hepatitis C virus genotypes in southern Taiwan: prevalence and clinical implications
Chuan-Mo Lee,Chuan-Mo Lee,Sheng-Nan Lu,Chao-Hung Hung,Wei-Chih Tung,Jing-Houng Wang,Hung-Da Tung,Chien-Hung Chen,Chien-Hung Chen,Tsung-Hui Hu,Chi-Sin Changchien,Wei-Jen Chen +11 more
TL;DR: The predominant genotypes in southern Taiwan were 1b and 2a/2c, and disease severity was associated with genotype 1b, and Disease severity was significantly correlated with older age, genotype1b, lower ALT levels and lower viral load.
The natural course of chronic hepatitis C: A comparison between patients with genotypes 1 and 2 hepatitis C viruses
Masakazu Kobayashi,Eiji Tanaka,Takeshi Sodeyama,Akihiko Urushihara,Akihiro Matsumoto,Kendo Kiyosawa +5 more
TL;DR: The results suggest that more severe progression of chronic hepatitis C is seen in patients showing genotype 1b compared with those with genotype 2, which may be related in part to the difference in pathogenicity between the two HCV genotypes.
Hepatic steatosis is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis C virus infection.
Kazuyuki Ohata,Keisuke Hamasaki,Kan Toriyama,Kojiro Matsumoto,Akira Saeki,Kenji Yanagi,Seigou Abiru,Yuichi Nakagawa,Masaya Shigeno,Seiji Miyazoe,Tatsuki Ichikawa,Hiroki Ishikawa,Kazuhiko Nakao,Katsumi Eguchi +13 more
TL;DR: The objective of this study was to determine the relation between hepatic steatosis and hepatocarcinogenesis in patients with chronic HCV infection.
Natural course of progression of liver fibrosis in Japanese patients with chronic liver disease type C--a study of 527 patients at one establishment.
TL;DR: Chronic hepatitis C is a progressive disease, and patients with genotype 1b, 2a and 2b have a similar rate of progression of liver fibrosis.