Heat shock, from bacteria to man

TL;DR: By testing a series of 5′ deletion mutants in this inducible transcription assay it was found that a sequence less than 70 bp long, directly upstream of the hsp70 gene, was essential for the heat or arsenite induction of transcription.

TL;DR: The availability of clones that contain RNA sequences that display several different patterns of abundance regulation makes possible studies on the mechanisms controlling the abundance of a wide variety of different RNA species during flagellar regeneration in Chlamydomonas.

TL;DR: It is proposed that an interplay between these RNA regions involving secondary structure formation is important in regulating translation initiation and that transient disruption of secondary structure represents a primary step of the heat shock response.

TL;DR: Hsp70 and Hsp40 are reviewed and the roles of these molecules in the synapse and cytoprotective functions of HSPs in stress tolerance and neurodegenerative diseases are referred to.