Open AccessJournal Article
Healing pattern of bone regeneration in membrane-protected defects: a histologic study in the canine mandible.
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TL;DR: The histologic evaluation showed that bone regeneration, once activated, progresses in a programmed sequence through a series of maturation steps, which closely resemble the pattern of bone development and growth.
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Abstract: In this study, standard and prototype reinforced e-PTFE membranes were used to evaluate the pattern of bone regeneration in membrane-protected defects in the mandibles of four dogs. Following a healing period of 2 and 4 months, control sites without membranes exhibited incomplete osseous healing with a persisting defect. Test sites with membranes demonstrated significantly better bone healing, although bone regeneration was not yet completed at 4 months. The histologic evaluation showed that bone regeneration, once activated, progresses in a programmed sequence through a series of maturation steps, which closely resemble the pattern of bone development and growth.
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Citations
Effect of two different bioabsorbable collagen membranes on guided bone regeneration: a comparative histomorphometric study in the dog mandible.
TL;DR: The CCM showed a limited beneficial effect on bone regeneration in membrane-protected defects in dog mandibles when healing was uneventful and increased complication rate with CCM requires a more detailed preclinical and clinical examination before any clinical recommendations can be made.
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Transcriptional profiling of “guided bone regeneration” in a critical‐size calvarial defect
TL;DR: The transcriptome associated with a maturing GBR-treated craniofacial bone defect is characterized by the down-regulation of the immuno-inflammatory response and up- regulation of skeletogeneis-, angiogenesis- and neurogenesis-associated genes.
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•Journal Article
"Sandwich" bone augmentation technique: rationale and report of pilot cases.
TL;DR: Results from this pilot case study indicated that the sandwichBone augmentation technique appears to enhance the outcomes of bone augmentation by using the positive properties of each applied material (autograft, DFDBA, hydroxyapatite, and collagen membrane).
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Localized Ridge Augmentation Using Guided Bone Regeneration
Alex M. Greenberg
- 01 Jan 2019
TL;DR: Careful presurgical clinical and radiographic evaluation is required to obtain the information needed regarding the bone quality and quantity as well as the vertical and horizontal dimensions.
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Evaluation of a prototype trilayer membrane (PTLM) for lateral ridge augmentation: an experimental study in the canine mandible
TL;DR: A biodegradable/bioresorbable prototype trilayer membrane (PTLM) consisting of two collagen layers and an internal polylactide layer for lateral ridge augmentation in conjunction with two different bone grafting materials cannot be recommended for clinical application.
77
References
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TL;DR: It was found that the differentiation features characteristic of mechanocytes of the source tissue are consistently retained by in vitro descendants of clonogenic cells, thus self-maintained precursors determined to differentiate into definite types of mechanocyte are present in postnatal life.
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•Journal Article
Localized ridge augmentation using guided bone regeneration. 1. Surgical procedure in the maxilla.
TL;DR: The currently used surgical procedure is presented through two case reports and the different aspects of the surgical technique needed to achieve a predictable success are discussed.
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