Handbook of statistical genetics
David J. Balding,M. J. Bishop,Chris Cannings +2 more
- 15 Jul 2004
- Iss: 1
678
TL;DR: This book presents a meta-analyses of the literature on quantitative and qualitative approaches to eukaryotic Gene Prediction and its applications to Genetics, and some of the techniques used in this work came from these reviews.
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Abstract: Editors' Preface. List of Contributors. BIOINFORMATICS. Chromosome Maps (T. Speed and H. Zhao). Statistical Significance in Biological Sequence Comparison (W. Pearson and T. Wood). Probabilistic Models for the Study of Protein Evolution (J. Thorne and N. Goldman). Statistical Approaches in Eukaryotic Gene Prediction (V. Solovyev). Protein Structure (W. Taylor). POPULATION GENETICS. Mathematical Models in Population Genetics (C. Neuhauser). Coalescent Theory (M. Nordborg). Inference Under the Coalescent (M. Stephens). Inferences from Spatial Population Genetics (F. Rousset). Analysis of Population Subdivision (L. Excoffier). Linkage Disequilibrium and Recombination (R. Hudson) EVOLUTIONARY GENETICS. Adaptive Molecular Evolution (Z. Yang). Genome Evolution (J. Brookfield). Virus Evolution (Y. Suzuki, et al.). Application of the Likelihood Function in Phylogenetic Analysis (J. Huelsenbeck and J. Bollback). Phylogenetics: Parsimony and Distance Methods (D. Penny and M. Hendy). GENETIC EPIDEMIOLOGY. Nonparametric Linkage (P. Holmans). The Transmission/Disequilibrium Test (W. Ewens and R. Spielman). Population Association (D. Clayton). Linkage Analysis (E. Thompson). ANIMAL AND PLANT GENETICS. Quantitative Trait Loci in Inbred Lines (R. Jansen). Mapping Quantitative Trait Loci in Outbred Pedigrees (I. Hoeschele). Inferences About Breeding Values (D. Gianola). Marker-Assisted Selection and Introgression (J. Whittaker). APPLICATIONS. Ethics in the Use of Statistics in Genetics (D. Beyleveld). Forensics (B. Weir). Pharmacogenetics (N. Schork, et al.). Statistical Basis of Risk Calculations (R. Chakraborty). Conservation Genetics (M. Beaumont). Genetic History of the Human Species (J. Relethford). Index
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Transcriptionally active LTR retrotransposons in Eucalyptus genus are differentially expressed and insertionally polymorphic.
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TL;DR: The authors' network-level analysis shows that DNA polymorphism exhibits the same polarity in the strength of purifying selection as previously detected at the divergence level, which points to the action of a general mechanism, whose action is neither organism specific nor evolutionary time dependent.
A population genetics model with recombination hotspots that are heterogeneous across the population.
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