Journal Article10.1309/MMAU-0QYH-7BHA-W8C2
Guidelines for interpreting EBER in situ hybridization and LMP1 immunohistochemical tests for detecting Epstein-Barr virus in Hodgkin lymphoma.
Margaret L. Gulley,Sally L. Glaser,Fiona E. Craig,Michael J. Borowitz,Risa B. Mann,Sarah J. Shema,Richard F. Ambinder +6 more
168
TL;DR: Four hematopathologists independently interpreted EBV-encoded RNA (EBER) and latent membrane protein 1 (LMP1) histochemical stains from 40 cases of Hodgkin lymphoma and then reviewed the stains as a group to resolve discrepancies and to develop interpretation guidelines.
read more
Abstract: Histochemical stains demonstrate Epstein-Barr virus (EBV) in approximately 40% of all Hodgkin
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Paper-based detection of Epstein-Barr virus using asymmetric polymerase chain reaction and gold silicon particles.
TL;DR: A paper-based lateral flow nucleic acid (LFNA) test platform was established in this paper using asymmetric polymerase chain ceaction (A-PCR) for signal amplification.
3
Epstein-Barr Virus-Associated Lymphomatoid Papules: A Sign of Immunosuppression Resembling Lymphomatoid Papulosis.
Madeline J. Hooper,Tessa M. LeWitt,Teresa Griffin,Joan Guitart +3 more
TL;DR: Clinopathologic presentations resembling lymphomatoid papulosis with atypical, large CD30-positive, EBV-positive cells could comprise first sign of potentially serious immunodeficiency and should prompt evaluation for EBV viremia.
3
Lmp-1 immunohistochemical detection of epstein - barr virus in lymphoma among sudanese patients
TL;DR: The aim of this study was to investigate the association of LMP-1 EBV in this tumors and showed a significant difference between case and control groups.
3
Herpesvirus-associated lymphomas: Investigations in humans and animal models.
TL;DR: This review deals with mechanisms of lymphoma formation regarding to the role of non-structural herpesvirus oncoproteins interfering with the regulation of cell division and/or exerting anti-apoptotic effects.
3
CD30 expression and Detection of Epstein-Barr Virus-Encoded Small RNA by Real-Time RT-PCR of Classic Hodgkin Lymphoma and Their Correlation with Risk Stratification
TL;DR: It is concluded that CD30 expression and EBV Infection correlate with risk assessment IPS-7 in CHL and may provide a stronger factor for risk assessment for the patient with HL.
References
•Book
Cancer Epidemiology and Prevention
David Schottenfeld,Joseph F. Fraumeni +1 more
- 01 Feb 1982
TL;DR: This is an account of cancer epidemiology has been expanded and contains new material on cancer biology, molecular epidemiology, preventive strategies and specific types and sites of cancer.
3.2K
Epstein‐Barr virus‐associated Hodgkin's disease: Epidemiologic characteristics in international data
Sally L. Glaser,Ruby J. Lin,Susan L. Stewart,Richard F. Ambinder,Ruth F. Jarrett,Pierre Brousset,Gorm Pallesen,Margaret L. Gulley,Gulfaraz Khan,Jane O'Grady,Michael Hummel,María Victoria Preciado,Hans Knecht,John K.C. Chan,Alexander Claviez +14 more
TL;DR: It is suggested that age, sex, ethnicity and the physiologic effects of poverty may represent biologic modifiers of the EBV association and confirmed that this association is strongly but variably linked to histologic subtype.
523
Hodgkin's disease and Epstein-Barr virus. Altered antibody pattern before diagnosis.
Nancy Mueller,Alfred S. Evans,Nancy L. Harris,George W. Comstock,Egil Jellum,Knut Magnus,Norman Orentreich,B. Frank Polk,Joseph H. Vogelman +8 more
TL;DR: The development of Hodgkin's disease may in some patients be preceded by enhanced activation of Epstein-Barr virus, and associations were stronger in serum samples obtained at least three years before diagnosis than in serum sample obtained closer to diagnosis.
449
Molecular Diagnosis of Epstein-Barr Virus-Related Diseases
TL;DR: Recent studies suggest a role for EBV viral load testing in nasopharyngeal carcinoma, Hodgkin's disease, and AIDS patients with brain lymphoma and further research is needed to define more fully the clinical utility of viral load tests in the full spectrum of EBV-associated diseases.
332