Green Tea Polyphenols Prevent Ultraviolet Light-Induced Oxidative Damage and Matrix Metalloproteinases Expression in Mouse Skin
TL;DR: GTP as a dietary supplement could be useful to attenuate solar UVB light-induced premature skin aging, and treatment resulted in inhibition of UVB-induced protein oxidation in vivo in mouse skin, a hallmark of photoaging.
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About: This article is published in Journal of Investigative Dermatology. The article was published on 01 Jun 2004. and is currently open access. The article focuses on the topics: Photoaging & GTP'.
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Citations
Anti-aging effects of high molecular weight proteoglycan from salmon nasal cartilage in hairless mice.
TL;DR: High molecular weight proteoglycan acts on gut immunity and improves skin by inhibiting surplus inflammatory cytokines produced by UVB irradiation, suggest results suggest.
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Dose-dependent in vitro inhibition of rabbit corneal matrix metalloproteinases by an extract of Pothomorphe umbellata after alkali injury
Luiz Fernando de Medeiros Monteiro de Barros,Paulo Sergio de Moraes Barros,Cristina Dislich Ropke,Vanessa Vitoriano da Silva,Tânia Cristina Higashi Sawada,Silvia Berlanga de Moraes Barros,Rubens Belfort +6 more
TL;DR: P. umbellata root crude extract can be useful as an alternative therapy to control MMP activity after corneal injury and promotes a 10-fold decrease in activity.
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Topical compositions for inhibiting matrix metalloproteases and providing antioxidative activities
Joseph D. Ceccoli,Brian Costello,James A. Hayward,Konstantinos M. Lahanas +3 more
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TL;DR: A topical composition according to the present invention for use in a skin care regimen that provides matrix metalloprotease (MMP) inhibiting activity, tissue inhibitor of METALOPROTEASE (TIMP) inducing activity, and immediate and delayed antioxidative activity is presented in this paper.
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Direct assessment by electron spin resonance spectroscopy of the antioxidant effects of French maritime pine bark extract in the maxillofacial region of hairless mice
Ayaka Yoshida,Fumihiko Yoshino,Masahito Tsubata,Motoya Ikeguchi,Takeshi Nakamura,Masaichi-Chang-il Lee +5 more
TL;DR: The ability of flavangenol to reduce reactive oxygen species levels in the circulation of the maxillofacial region suggests that this extract may be beneficial for skin protection from exposure to ultraviolet irradiation.
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References
Mechanisms of photoaging and chronological skin aging
Gary J. Fisher,Sewon Kang,James Varani,Zsuzsanna Bata-Csorgo,Yinsheng Wan,Subhash C. Datta,John J. Voorhees +6 more
TL;DR: This article reviews the current understanding and presents new data about the molecular pathways that mediate skin damage by UV irradiation and by the passage of time and reveals that chronological aging and photoaging share fundamental molecular pathways.
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UV-light-induced signal cascades and skin aging
Laure Rittié,Gary J. Fisher +1 more
TL;DR: Examining molecular responses of human skin to UV irradiation provides not only a framework for understanding mechanisms involved in skin aging, but also may help in development of new clinical strategies to impede chronological and UV-induced skin aging.
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Matrix metalloproteinases in skin
TL;DR: The role of MMPs and TIMPs in human skin based on new observations on the regulation of the expression of M MPs, on their substrate specificily, and MMP expression in physiologic and pathologic conditions of skin involving matrix remodeling are discussed.
639
Wide Distribution of [3H](-)-epigallocatechin Gallate, a Cancer Preventive Tea Polyphenol, in Mouse Tissue
TL;DR: The results suggest that frequent consumption of green tea enables the body to maintain a high level of tea polyphenols and this paper is the first pharmacological evidence of a wide distribution of [3H]EGCG in mouse organs, indicating a similar wide range of target organs for cancer prevention in humans.
Ultraviolet-B Irradiation and Matrix Metalloproteinases
TL;DR: This review will focus on UVB‐triggered induction of matrix metalloproteinases, the so far identified components of theUVB‐modulated signal transduction pathway(s), and the UVB irradiation‐associated generation of reactive oxygen species (ROS).
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