Graphical analysis of PET data applied to reversible and irreversible tracers.

TL;DR: Although they are based on quite different imaging processes, the terms functional and molecular imaging are often used interchangeably, due to a lack of consensus regarding their definitions.

TL;DR: Patients with glucose transporter (GLUT) type I deficiency are haploinsufficient in SLC2A1, the gene that encodes the GLUT isoforms present in red blood cells, endothelial cells of the blood–brain barrier, and astrocytes, and it is unknown how this impacts other aspects of brain development and even postdevelopment brain function.

TL;DR: Investigation of the sensitivity of the bi-linear reference tissue method to statistical noise, with special regard to the assessment of receptor occupancy, found the equilibrium specific-to-non-specific partition coefficient V′′3 was significantly underestimated.

TL;DR: The results demonstrate that the quantification method as well as the controls used can be important for interpreting the uptake in tumours of the medium-sized protein ligand AnxA5 and its use in monitoring the effects of therapy on cell death in the tumours.

TL;DR: General equations are derived that can be used to analyze tissue uptake data when the blood–plasma concentration of the test substance cannot be easily measured and for situations when trapping of theTest substance is incomplete and for a combination of these two conditions.

TL;DR: In this paper, the authors proposed a graphical method for determining the distribution volume ratio (DVR), which is a linear function of receptor availability, which does not require blood sampling and is widely used as a model parameter in imaging studies.

TL;DR: It can be shown that, for many systems, linearity is effectively reached some time before this, and this method provides an easy, rapid method for comparison of the reproducibility of repeated measures in a single subject, for longitudinal or drug intervention protocols, or for comparing experimental results between subjects.

TL;DR: An infusion protocol consisting of bolus plus continuous infusion of CF was designed and applied and has the potential to shorten scan time and simplify the acquisition and processing of scan and blood data.