Journal Article10.1016/J.JCLINEPI.2010.04.026
GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables
Gordon H. Guyatt,Andrew D Oxman,Elie A. Akl,Regina Kunz,Gunn Elisabeth Vist,Jan Brozek,Susan L Norris,Yngve Falck-Ytter,Paul Glasziou,Hans deBeer,Roman Jaeschke,David Rind,Joerg J Meerpohl,Philipp Dahm,Holger J. Schünemann +14 more
TL;DR: The GRADE process begins with asking an explicit question, including specification of all important outcomes, and provides explicit criteria for rating the quality of evidence that include study design, risk of bias, imprecision, inconsistency, indirectness, and magnitude of effect.
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About: This article is published in Journal of Clinical Epidemiology. The article was published on 01 Apr 2011. The article focuses on the topics: Evidence-based medicine & Evidence-based practice.
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Effects of home telemonitoring interventions on patients with chronic heart failure: an overview of systematic reviews.
TL;DR: Evidence from high-quality reviews with meta-analysis indicated that taken collectively, home telemonitoring interventions reduce the relative risk of all-cause mortality and HF-related hospitalizations, suggesting that further research is very likely to have an important impact on confidence in the observed estimates of effect.
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Selective serotonin reuptake inhibitors versus placebo in patients with major depressive disorder. A systematic review with meta-analysis and Trial Sequential Analysis
Janus Christian Jakobsen,Kiran Kumar Katakam,Anne Schou,Signe Gade Hellmuth,Sandra Elkjær Stallknecht,Katja Biering Leth-Møller,Maria Iversen,Marianne Bjørnø Banke,Iggiannguaq Juhl Petersen,Sarah Louise Klingenberg,Jesper Krogh,Sebastian Elgaard Ebert,Anne Timm,Jane Lindschou,Christian Gluud +14 more
TL;DR: SSRIs might have statistically significant effects on depressive symptoms, but all trials were at high risk of bias and the clinical significance seems questionable, and the potential small beneficial effects seem to be outweighed by harmful effects.
Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents – assessment of adverse events in non‐randomised studies
Ole Jakob Storebø,Nadia Pedersen,Erica Ramstad,M.L. Kielsholm,SS Nielsen,Helle B Krogh,Carlos Renato Moreira-Maia,Frederik L Magnusson,Mathilde Holmskov,Trine Gerner,Maria Skoog,Susanne Rosendal,Camilla Groth,Donna Gillies,Kirsten Buch Rasmussen,Dorothy Gauci,Morris Zwi,Richard Kirubakaran,Sasja Jul Håkonsen,Lise Aagaard,Erik Simonsen,Christian Gluud +21 more
TL;DR: A systematic review of randomised clinical trials (RCTs) for methylphenidate treatment for children and adolescents with ADHD demonstrated no increase in serious adverse events, but a high proportion of participants suffered a range of non-serious adverse events.
Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder: Synopsis of the Kidney Disease: Improving Global Outcomes 2017 Clinical Practice Guideline Update
Markus Ketteler,Geoffrey A. Block,Pieter Evenepoel,Masafumi Fukagawa,Charles A. Herzog,Linda M. McCann,Sharon M. Moe,Rukshana Shroff,Marcello Tonelli,Nigel D Toussaint,Marc G. Vervloet,Mary B. Leonard +11 more
TL;DR: This synopsis focuses on diagnosis of CKDMBD and management of serum phosphate, calcium, and PTH levels in adults and areas in which controversy and knowledge gaps exist.
The effect of the work environment on future sleep disturbances: a systematic review
Steven J. Linton,Göran Kecklund,Karl A. Franklin,Lena C. Leissner,Børge Sivertsen,Eva Lindberg,Anna C. Svensson,Sven Ove Hansson,Örjan Sundin,Jerker Hetta,Cecilia Björkelund,Charlotte Hall +11 more
TL;DR: It is concluded that psychosocial work factors and the scheduling of work have an impact on sleep disturbances and this might be utilized in the clinic as well as for planning work environments.
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References
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Cochrane Handbook for Systematic Reviews of Interventions
Abstract: The Cochrane Handbook for Systematic Reviews of Interventions is the official document that describes in detail the process of preparing and maintaining Cochrane systematic reviews on the effects of healthcare interventions.
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
TL;DR: The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
What is “quality of evidence” and why is it important to clinicians?
Gordon H. Guyatt,Andrew D Oxman,Regina Kunz,Gunn Elisabeth Vist,Yngve Falck-Ytter,Holger J. Schünemann +5 more
TL;DR: Guideline developers use a bewildering variety of systems to rate the quality of the evidence underlying their recommendations as mentioned in this paper, some are facile, some confused, and others sophisticated but complex.
•Book
Clinical practice guidelines : directions for a new program
Marilyn J. Field,Kathleen N. Lohr +1 more
- 01 Jan 1990
TL;DR: This clinical practice guidelines directions for a new program, it will really give you the good idea to be successful.
1.8K
Going from evidence to recommendations
Gordon H. Guyatt,Andrew D Oxman,Regina Kunz,Yngve Falck-Ytter,Gunn Elisabeth Vist,Alessandro Liberati,Holger J. Schünemann +6 more
TL;DR: The GRADE system classifies recommendations made in guidelines as either strong or weak, and the meaning of these descriptions and their implications for patients, clinicians, and policy makers are explored.