Ginsenoside derivatives and quality characteristics of fermented ginseng using lactic acid bacteria
Bok-Hee Kang,Kun-Jae Lee,Sang-Sun Hur,Dong-Sun Lee,Sang-Han Lee,Ki-Sun Shin,Jin-Man Lee +6 more
- 30 Aug 2013
- Vol. 20, Iss: 4, pp 573-582
TL;DR: In this article, the authors investigated the bioconversion of ginsenoside, as well as the quality characteristics of fermented ginseng, by using lactic acid bacteria.
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Abstract: This study was done in order to investigate the bioconversion of ginsenoside, as well as the quality characteristics of fermented ginseng, by using lactic acid bacteria. Quality characteristics such as the thin layer chromatography(TLC) pattern, ginsenosides, total phenolic content, electron donating ability, and total sugar of fermenting ginseng and red ginseng were analyzed. The ginsenoside Rg2r, Rh2s and Rh2r of the fermented ginseng and red ginseng for 65 hours at a temperature of were not detected. The ginsenoside Rg1 and Re contents have decreased, while the Rh1, Rg2s, Rd, Rg3r, and Rg3s have increased due to fermentation. The ginsenoside Rg3 of the fermented red ginseng has increased and the contents were (control ). The total phenolic content and electron donating ability of the red ginseng have totally decreased after 7 days of fermentation. The total phenolic contents of the fermented ginseng and red ginseng with different lactic acid bacteria did not show any tendency as different strains. The electron donating ability of the fermented ginseng has increased; however, the electron donating ability of the red ginseng has decreased. The total sugars of the fermented ginseng and red ginseng with different lactic acid bacteria have also decreased.
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Citations
Biotransformation of major ginsenosides in ginsenoside model culture by lactic acid bacteria
TL;DR: Ginsenosides Rb1, Rb2, Rc, and Re continuously decreased, whereas gINSenosides Rd, Rg1, and Rg2 increased after 1–2 d of fermentation, which may provide new insights into the metabolism of ginsenoside and can clarify the metabolic changes in ginsene biotransformed by LAB.
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Changes in the ginsenoside content during the fermentation process using microbial strains
TL;DR: It is confirmed that fermentation had occurred using only microbial strains and the changes in the ginsenoside content and the role of microbial strains in the fermentation process were confirmed.
33
Effect of Lactic Acid Bacteria on the Pharmacokinetics and Metabolism of Ginsenosides in Mice.
TL;DR: In this article, the effect of lactic acid bacteria (LAB) on in vitro and in vivo metabolism and the pharmacokinetics of ginsenosides in mice was investigated, and it was shown that the supplementation of LAB with oral administrations of RGE would help increase plasma concentrations of deglycosylated ginsenesides such as CK, PPD, and PPT.
19
Metabolite profiling of fermented ginseng extracts by gas chromatography mass spectrometry.
TL;DR: The results suggest that a metabolomics approach based on GC-MS can be a useful tool to understand ginseng fermentation and evaluate the fermentative characteristics of starter cultures.
17
Concomitant Administration of Red Ginseng Extract with Lactic Acid Bacteria Increases the Plasma Concentration of Deglycosylated Ginsenosides in Healthy Human Subjects
TL;DR: In this paper , the authors investigated the interactions between red ginseng extract (RGE) and lactic acid bacteria (LAB) co-administration with regard to in vitro and in vivo deglycosylation metabolism and the pharmacokinetics of ginsenosides.
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