Journal Article10.1016/S0006-2952(99)00212-9
Ginseng pharmacology: Multiple constituents and multiple actions
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TL;DR: This commentary aims to review selected effects of ginseng and ginsenosides and describe their possible modes of action, structural and functional relationship to steroids, and potential targets of action.
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About: This article is published in Biochemical Pharmacology. The article was published on 01 Dec 1999. The article focuses on the topics: Asian Ginseng & Ginseng.
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Citations
Ginseng administration protects skeletal muscle from oxidative stress induced by acute exercise in rats.
J. Voces,A.C. Cabral de Oliveira,Julio G. Prieto,L. Vila,A.C. Perez,Igor D.G. Duarte,Ana I. Alvarez +6 more
TL;DR: The administration of ginseng extract was able to protect muscle from exercise-induced oxidative stress irrespective of fiber type and showed a membrane stabilizing capacity of the extract.
Systematic profiling and comparison of the lipidomes from Panax ginseng, P. quinquefolius, and P. notoginseng by ultrahigh performance supercritical fluid chromatography/high-resolution mass spectrometry and ion mobility-derived collision cross section measurement.
TL;DR: A lipidomics platform by integrating ultrahigh performance supercritical fluid chromatography/quadrupole time-of-flight mass spectrometry and collision cross section (CCS) measurement using ion mobility spectroscopy/time-of the flight mass spectromaetry (IMS/QTOF-MS), aiming to enhance the profiling performance and identification reliability of lipids.
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Non-genomic effects of ginsenoside-Re in endothelial cells via glucocorticoid receptor
TL;DR: Ginsenoside‐Re (Re), a pharmacological active component of ginseng, is a functional ligand of glucocorticoid receptor (GR) and the activated GR induces rapid Ca2+ influx and NO production in endothelial cells.
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Ultra-performance liquid chromatography and time-of-flight mass spectrometry analysis of ginsenoside metabolites in human plasma.
Chong-Zhi Wang,Karen E. Kim,Guang-Jian Du,Lian Wen Qi,Lian Wen Qi,Xiao-Dong Wen,Xiao-Dong Wen,Ping Li,Brent A. Bauer,Marc Bissonnette,Mark W. Musch,Eugene B. Chang,Chun-Su Yuan +12 more
TL;DR: The gradual decrease of Rb1 levels and the delayed increase in levels of C-K observed in human subjects supported previous reports that enteric microbiota played a key role in transforming Rb2 to C-k, and helped clarify the role of intestinal microbiota in ginsenosides transformed by intestinal microbiota.
Pharmacological Effects of Ginseng on Liver Functions and Diseases: A Minireview
TL;DR: The pharmacological effects of ginseng and ginsenosides on the liver functions are outlined and a wide array of beneficial role in the regulation of regular liver functions and the treatment of liver disorders of acute/chronic hepatotoxicity, hepatitis, hepatic fibrosis/cirrhosis, hepatocellular carcinoma, and so on.
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