Journal Article10.1007/S11121-006-0042-5
Genetic Contribution to Suicidal Behaviors and Associated Risk Factors among Adolescents in the U.S.
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TL;DR: Gender differences found in the heritability of some suicide risk factors suggest these genetic contributions are gender specific, and risk factors for suicidal behaviors among adolescents may be heritable.
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Abstract: This paper examines genetic contribution to suicidal behaviors and other risk factors associated with suicidal behavior among adolescents in the U.S. Using adolescent twin data in the National Longitudinal Study of Adolescent Health (N = 1448), we compared concordance in suicidal ideation and attempt among monozygotic (MZ) and dizygotic (DZ) twins. Heritability of risk factors for suicidal behaviors also was examined using Pearson correlation and mixed-model analyses. A trend of higher concordance in suicidal ideation and attempt was found among MZ than DZ twins but the difference was not statistically significant by the stringent test of bootstrapping analysis. Evidence of heritability was found for several suicide risk factors. The percentage of variance explained by heritability was larger among female twins for depression, aggression, and quantity of cigarettes smoked in comparison to heritability estimates for male twins. However, estimated heritability was larger among male than female twins for alcohol use and binge drinking. Heritability influence was negligible among both sexes for other drug use. Risk factors for suicidal behaviors among adolescents may be heritable. Gender differences found in the heritability of some suicide risk factors suggest these genetic contributions are gender specific. Future research examining potential interactions between expression of genetic influence and particular environmental contexts may enhance prevention and intervention efforts.
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Genetic and environmental influences on cannabis use initiation and problematic use: a meta‐analysis of twin studies
Karin J. H. Verweij,Brendan P. Zietsch,Brendan P. Zietsch,Michael T. Lynskey,Sarah E. Medland,Michael C. Neale,Nicholas G. Martin,Dorret I. Boomsma,Jacqueline M. Vink +8 more
TL;DR: Vulnerability to both cannabis use initiation and problematic use was influenced significantly by A, C and E, and there was a trend for a greater C and lesser A component for Cannabis use initiation compared to problematic use for females.
Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions.
Bojan Mirkovic,Claudine Laurent,Marc-Antoine Podlipski,Thierry Frebourg,David Cohen,Priscille Gerardin +5 more
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TL;DR: This chapter reviews the recent evidence of genetic and environmental influences on human aggression and suggests that not all individuals will be affected to the same degree by experiences and exposures, and that genetic predispositions may have different effects depending on the environment.
References
Deaths: leading causes for 2002.
Robert N Anderson,Betty L. Smith +1 more
- 07 Mar 2005
TL;DR: This report supplements the annual report of final mortality statistics and presents final 2002 data on the 10 leading causes of death in the United States by age, race, sex, and Hispanic origin.
Suicidal behaviour: an epidemiological and genetic study
Dixie J. Statham,Andrew C. Heath,Pamela A. F. Madden,Kathleen K. Bucholz,Laura J. Bierut,Stephen H. Dinwiddie,Wendy S. Slutske,Michael P. Dunne,N. G. Martin +8 more
TL;DR: Risk of persistent suicidal thoughts and suicide attempts is determined by a complex interplay of psychiatric history, neuroticism, traumatic life experiences, genetic vulnerability specific for suicidal behaviour and sociocultural risk or protective factors.
Attachment and Dependency in Developmental Perspective.
TL;DR: In this paper, the authors examined the relationship between infant-caregiver relations and later overdependency by assessing children with varying attachment histories in a preschool setting, and found that children who had been securely attached were significantly lower on all these measures and significantly higher on "seeking attention in positive ways."
381
Association of adolescent risk behaviors with mental health symptoms in high school students.
TL;DR: Female gender had greater than threefold increased odds of reporting depression/stress and other associations, with some gender differences, include older age, physical fights, non-use of birth control, lack of a healthy diet, and use of tobacco.
352
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