Open AccessDissertation
Gene expression profiling of mesenteric lymph nodes in red deer (Cervus elaphus) resilient or susceptible to Johne's disease
Courtenay Suzanne Ranson
- 01 Jan 2014
TL;DR: It is suggested that within the context of a youth-services agency using a mobile app to assess the needs of vulnerable adults is a viable process and should be considered a natural progression.
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Abstract: ..........................................................................................................................ii Acknowledgements ....................................................................................................... iii Table of
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References
Longitudinal Pathogenesis Study of Young Red Deer (Cervus elaphus) after Experimental Challenge with Mycobacterium avium subsp. paratuberculosis (MAP).
TL;DR: Clinical, immunological and pathological changes over a 50-week period in fourteen 4-month-old red deer that received heavy oral challenge with Mycobacterium avium subsp.
Biomarker Discovery via RT-qPCR and Bioinformatical Validation
Christiane Becker,Irmgard Riedmaier,Michael W. Pfaffl +2 more
- 01 Jan 2013
TL;DR: There is a growing interest in life science research in the use of expressed transcripts that form the basis of biological markers (biomarkers) and in addressing some of the challenging statistical issues that arise when attempting to validate them.
3
Transitions in immune responses to Mycobacterium paratuberculosis
TL;DR: The current knowledge of T cell immune responses in M. paratuberculosis infection is reviewed based upon clinical studies and research using mouse models to provide protective immunity and prevent progression of the disease.
Does a Th1 over Th2 dominancy really exist in the early stages of Mycobacterium avium subspecies paratuberculosis infections
Douglas J. Begg,K. de Silva,Nicole Carter,Karren M. Plain,Auriol C. Purdie,Richard Whittington +5 more
TL;DR: The immune response in sheep to Mycobacterium avium subspecies paratuberculosis infections is examined, specifically the antigen-specific interferon gamma (IFN-γ) and antibody responses as surrogates of T helper-1 and Th2 immunity.
Mesenteric lymph nodes at the center of immune anatomy
Andrew J. Macpherson,Karen Smith +1 more
TL;DR: Recent work shows that the mesenteric lymph nodes (MLNs) are the key site for tolerance induction to food proteins and that they also act as a firewall to prevent live commensal intestinal bacteria from penetrating the systemic immune system.