Patent
Gene data processing method and gene data processing device
Zhou Fengfeng,Zhao Miaomiao +1 more
- 11 Mar 2015
6
TL;DR: In this paper, a gene data processing method and a data processing device are described. And the method comprises the following steps: receiving gene data of a specified feature type of a reference population, preprocessing the gene data to obtain standardized gene data; performing feature gene selection on the standardized gene dataset by a LASSO method to obtain feature gene data, upon a cross validation method, dividing a sample set of the feature gene dataset into test samples and training samples, injecting the training samples into a classifier to obtain a trained classifier; injecting the test samples into the trained class
read more
Abstract: The embodiment of the invention discloses a gene data processing method and a gene data processing device. The method comprises the following steps: receiving gene data of a specified feature type of a reference population; preprocessing the gene data to obtain standardized gene data; performing feature gene selection on the standardized gene data by a LASSO method to obtain feature gene data; upon a cross validation method, dividing a sample set of the feature gene data into test samples and training samples; injecting the training samples into a classifier to obtain a trained classifier; injecting the test samples into the trained classifier; performing feature classification on the test samples, and performing statistics on the classification accuracy of the classifier. According to the gene data processing method and the gene data processing device provided by the embodiment of the invention, the accuracy of the feature gene selection can be improved, and the influence of the selection of the test samples and the training samples on the classification accuracy is lowered.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Patent
Small sample gene expression data classification method based on gene big data
Hao Zhifeng,Xu Baiyan,Cai Ruichu,Wen Wen,Zhang Xiaowen,Lin Yinxian,Wang Riyu,Chen Bingfeng +7 more
- 03 Aug 2016
TL;DR: In this article, a small sample gene expression data classification method based on gene big data is proposed, which comprises the technical steps of determining training sample gene expressions data and class labels, and building a matrix; calculating the L+1 order evaluation score according to the L order frequency number statistical result and the 2 order frequency numbers statistical result, and removing an infrequent set with the evaluation score smaller than the threshold value.
6
Patent
12-gene expression classifier for predicting colonic adenocarcinoma prognosis, and establishment method for classifier
Wang Jun,Lu Xiao,Gu Kai,Hao Wenshan,Shi Qiping +4 more
- 12 Dec 2017
TL;DR: In this paper, a gene expression classifier for predicting colonic adenocarcinoma prognosis, and an establishment method for the classifier were revealed. But the authors did not reveal the classification of the cancer types.
3
Patent
Genetic and environmental correlation-based colorectal cancer data model analysis method
Le Zhang,Chunqiu Zheng,Tian Li,Ziyuan Zhou,Badong Chen,Lei Xing,Tingting Li +6 more
- 18 Aug 2017
TL;DR: In this article, a genetic and environmental correlation-based colorectal cancer data model analysis method is proposed, which comprises the steps of receiving CRC data of a specified feature type of a reference population; preprocessing the data to obtain standardized data; based on the standardized data, classifying the data; performing feature selection on each subclass by using a sparse principal component analysis method, an information entropy method and/or a Relief method; obtaining an intersection of three methods by using Venn diagram, and obtaining features with remarkable difference by using U test; and dividing a feature gene
2
Patent
Markov carpet embedded type feature selection method based on packaging
Jing Yang,Aiguo Wang,Ning An +2 more
- 30 Dec 2015
TL;DR: The Markov carpet embedded type feature selection method is characterized by being carried out according to the following steps: 1, acquiring an optimal feature by using a five-fold cross validation method; 2, judging whether the optimal feature is a null set not; if so, finishing feature selection; otherwise, updating a feature subset; 3, deleting redundancy features by using the Markov Carpet method so as to update a feature vector; and 4, finishing the feature selection as discussed by the authors.
2
Patent
Method for survival time analysis fusing DNA methylation characteristics
Zou Jianxiao,Yang Fei,Fan Shicai,Xu Hongbing +3 more
- 20 Oct 2017
TL;DR: In this paper, a method for survival time analysis fusing DNA methylation characteristics was proposed, where three kinds of characteristic data are obtained from a TCGA database, some characteristics which are of great importance to cancers are obtained by performing characteristic selection on the three kinds and then COX regression is performed on these characteristics to obtain a regression model.
1