Open AccessJournal Article
Gastroesophageal reflux disease symptoms on antisecretory therapy: acid, non-acid, or no GERD
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TL;DR: The approach to evaluation and management of cases of refractory or difficult gastroesophageal reflux disease is the subject of this state-of-the-art review.
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Abstract: A clinically important subset of patients with erosive esophagitis will not attain adequate symptom relief and healing on once-a-day proton pump inhibitor therapy This is especially true in patients with frequent and nocturnal heartburn and in those with Los Angeles Grades C and D erosive esophagitis The approach to evaluation and management of cases of refractory or difficult gastroesophageal reflux disease is the subject of this state-of-the-art review
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Citations
Evaluation of the gastrointestinal clinical, endoscopic, and histological findings in patients with bile reflux diseases: A cross-sectional study
Sabeha Al-Bayati,Ahmed Sahir Alnajjar +1 more
- 01 Jan 2019
TL;DR: Bile reflux disease was more common in young female and cholecystectomy was common risk factor, and the most common endoscopic findings were gastric erythema.
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Bolus retention in hiatal hernia identified by high-resolution esophageal manometry with impedance
TL;DR: Pressure profiles in patients with HH with BR in the hernia are compared to those with bolus clearance through theHernia using high‐resolution esophageal manometry with impedance (HREMI) to determine the prevalence of bolus retention.
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Potential Options to Optimize Therapy of Gastroesophageal Reflux Disease with Proton Pump Inhibitors
TL;DR: The use of PPIs with the strongest antisecretory properties might reveal to be more adequate and cost-effective, particularly for this indication, as this condition appears to be less responsive to PPIs.
Tailored antireflux surgery.
TL;DR: Good results of antireflux surgery with zero mortality and low morbidity can be achieved even in the elderly (more frequent use of incomplete Toupet’s wrap).
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