Functional Performance of Human Cardiosphere-derived Cells Delivered in an In Situ Polymerizable Hyaluronan-Gelatin Hydrogel
Ke Cheng,Agnieszka Blusztajn,Deliang Shen,Deliang Shen,Tao-Sheng Li,Baiming Sun,Giselle Galang,Thomas I. Zarembinski,Glenn D. Prestwich,Eduardo Marbán,Rachel R Smith,Linda Marbán +11 more
TL;DR: A CDC/hydrogel formulation suitable for catheter-based intramyocardial injection exhibits superior engraftment and functional benefits relative to naked CDCs.
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About: This article is published in Biomaterials. The article was published on 01 Jul 2012. and is currently open access.
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Citations
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TL;DR: CardioCluster delivery improves cell retention following intramyocardial injection with preservation of long-term cardiac function relative to monolayer-cultured cells when tested in an experimental murine infarction model followed for up to 20 weeks post-challenge.
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