Functional DNA nanotechnology: emerging applications of DNAzymes and aptamers.

TL;DR: Here, this work reviews DNA strand-displacement-based devices, and looks at how this relatively simple mechanism can lead to a surprising diversity of dynamic behaviour.

TL;DR: This work aims to review different strategies of surface modification and functionalization of inorganic colloidal nanoparticles with a special focus on the material systems gold and semiconductor nanoparticles, such as CdSe/ZnS.

TL;DR: This review selectively analyzes current advances in the field of graphene bioapplications, and focuses on the biofunctionalization of graphene for biological applications, fluorescence-resonance-energy-transfer-based biosensor development by using graphene or graphene-based nanomaterials, and the investigation of grapheneor graphene- based nanommaterials for living cell studies.

TL;DR: The use of catalytic nucleic acids for amplified biosensing was accomplished by designing aptamer-DNAzyme conjugates that combine recognition units and amplifying readout units as in integrated biosensing materials.

TL;DR: It is reported that double-helical DNA constraints can be used to control the conformation of another molecule, RNA, when a covalently attached DNA constraint is structurally incompatible with the native Mg2+-dependent RNA conformation.

TL;DR: In these experiments, two short 10to 20-nucleotide DNA strands were covalently attached through their 5’-termini to specific nucleotides within the autonomously folding 160-n nucleotide P4–P6 RNA domain (molecular weight 51000).

TL;DR: A new improved design is reported that allows fast (<10 min) detection of Pb(2+) at ambient temperature and demonstrates that fundamental understanding of the DNAzyme biochemistry and nanoparticle science can lead to dramatically improved colorimetric sensors.