Journal Article10.1002/MRM.1910340409
Functional connectivity in the motor cortex of resting human brain using echo-planar MRI.
9.7K
TL;DR: It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.
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Abstract: An MRI time course of 512 echo-planar images (EPI) in resting human brain obtained every 250 ms reveals fluctuations in signal intensity in each pixel that have a physiologic origin. Regions of the sensorimotor cortex that were activated secondary to hand movement were identified using functional MRI methodology (FMRI). Time courses of low frequency (< 0.1 Hz) fluctuations in resting brain were observed to have a high degree of temporal correlation (P < 10(-3)) within these regions and also with time courses in several other regions that can be associated with motor function. It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.
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References
Inferring Correlation Networks from Genomic Survey Data
TL;DR: SparCC as mentioned in this paper is a new approach that is capable of estimating correlation values from compositional data, which is used to infer a rich ecological network connecting hundreds of interacting species across 18 sites on the human body.
Nucleic acid junctions and lattices
TL;DR: It appears to be possible to generate covalently joined three-dimensional networks of nucleic acids which are periodic in connectivity and perhaps in space.
2.4K
A practical solution to the pervasive problems of p values.
TL;DR: The BIC provides an approximation to a Bayesian hypothesis test, does not require the specification of priors, and can be easily calculated from SPSS output.
•Book
Insomnia: Psychological Assessment and Management
Charles M. Morin
- 21 May 1993
TL;DR: For instance, this article found that chronic insomnia affects from 20 to 40 percent of all adults, particularly women and the elderly, yet there is widespread belief that chronic chronic insomnia is not really a medical problem and that it can be treated only w
2.4K
Social-information-processing factors in reactive and proactive aggression in children's peer groups
Kenneth A. Dodge,John D. Coie +1 more
TL;DR: Three studies supported the hypothesis that attributional biases and deficits are related to reactive aggression but not to proactive aggression, which was hypothesized to occur as a function of hostile attributional bias and intention-cue detection deficits.
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