Functional clustering and lineage markers: Insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populations
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TL;DR: It is demonstrated that it is possible to identify very tight expression signatures associated specifically with embryonic stem cells, mesenchymal cells and hematopoietic lineages, and validated the prediction that gene function can be inferred by co-expression.
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About: This article is published in Genomics. The article was published on 01 Jun 2010. and is currently open access. The article focuses on the topics: Lineage markers & Gene expression profiling.
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TL;DR: Detailed polling of transcription start and termination sites and analysis of previously unidentified full-length complementary DNAs derived from the mouse genome provide a comprehensive platform for the comparative analysis of mammalian transcriptional regulation in differentiation and development.
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A Gene Network Regulating Lysosomal Biogenesis and Function
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