From the Chicago MeetingsSarcopenia

TL;DR: This cross-sectional study does not allow a definitive conclusion about the relationship between ghrelin levels and sarcopenia in elderly people, and further large prospective studies are needed to test this hypothesis.

TL;DR: It is proposed that these two models of interaction are complementary and intertwined providing for a new frontier for the investigation of how bone–muscle cross talk could be fully explored for the targeting of new therapies for musculoskeletal diseases.

TL;DR: The finding that muscle strength and cross-sectional area are reduced in SCH and improved after treatment lends support for the clinical decision to treat rather than observe this condition.

TL;DR: A program of research is proposed to evaluate whether there is some subset of breast cancer survivors for whom prevention or rehabilitation of functional status declines is needed, as well as development of targeted, mechanistically driven interventions.

TL;DR: Some of the first estimates of the extent of the public health problem posed by sarcopenia are provided, independent of ethnicity, age, morbidity, obesity, income, and health behaviors.

TL;DR: High-intensity resistance exercise training is a feasible and effective means of counteracting muscle weakness and physical frailty in very elderly people, in contrast to multi-nutrient supplementation without concomitant exercise, which does not reduce muscle weakness orPhysical frailty.

TL;DR: The studies reveal that endogenous IL-6 plays a crucial antiinflammatory role in both local and systemic acute inflammatory responses by controlling the level of proinflammatory, but not antiinflammatory, cytokines, and that these antiinflammatory activities byIL-6 cannot be compensated for by IL-10 or other IL- 6 family members.

TL;DR: Results indicate a gradual decrease in size/volume with advancing age, accompanied by a replacement by fat and connective tissue.