Journal Article10.1016/S0024-3205(97)01008-4
Free Cortisol Levels after Awakening: A Reliable Biological Marker for the Assessment of Adrenocortical Activity
Jens C. Pruessner,Oliver T. Wolf,Dirk H. Hellhammer,Angelika Buske-Kirschbaum,K. von Auer,Silke Jobst,F. Kaspers,Clemens Kirschbaum +7 more
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TL;DR: Early morning cortisol levels can be a reliable biological marker for the individual's adrenocortical activity when measured repeatedly with strict reference to the time of awakening, in contrast to single assessments at fixed times.
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About: This article is published in Life Sciences. The article was published on 21 Nov 1997. The article focuses on the topics: Cortisol awakening response & Upon Awakening.
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Citations
Impact of gender, menstrual cycle phase, and oral contraceptives on the activity of the hypothalamus-pituitary-adrenal axis.
TL;DR: Although men seem to have a stronger hypothalamic drive in response to stressful stimulation than women, differences in salivary-free cortisol levels, at least in part, may be explained by estradiol-induced changes in corticosteroid-binding protein levels.
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Salivary cortisol as a biomarker in stress research.
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The cortisol awakening response (CAR): Facts and future directions
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Cortisol awakening response and psychosocial factors: a systematic review and meta-analysis.
Yoichi Chida,Andrew Steptoe +1 more
TL;DR: It is found that the increase in cortisol following waking (CARi), and the integrated volume of cortisol released over the waking period (CARauc), was positively associated with job stress and general life stress and negatively related to posttraumatic stress syndrome.
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The effects of sex and hormonal status on the physiological response to acute psychosocial stress.
TL;DR: It is hypothesised that sex differences in HPAA and autonomic nervous system responses to acute psychosocial stress have to a great deal been driven by the need to protect the fetus from the adverse effects of maternal stress responses, in particular excess glucocorticoid exposure.
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TL;DR: This overview intends to give a comprehensive introduction to the method of salivary cortisol assessment and to briefly discuss its application in different scientific disciplines.
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Age, disease, and changing sex hormone levels in middle-aged men: results of the Massachusetts Male Aging Study.
TL;DR: Subgroup analyses suggested that obese subjects might be responsible for much of the group difference in androgen level, and serum concentrations of estrogens and cortisol did not change significantly with age or differ between groups.
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Synthesis of a cortisol-biotin conjugate and evaluation as a tracer in an immunoassay for salivary cortisol measurement
TL;DR: A simple-to-perform synthesis yielded a conjugate suitable for use as a tracer in immunoassays for cortisol measurement and showed excellent correlation with a commercially available radioimmunoassay adapted for salivary cortisol measurement.
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Consistent sex differences in cortisol responses to psychological stress.
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