Fractional CO2 laser for treatment of stress urinary incontinence.
Fariba Behnia-Willison,Tran Nguyen,Behrang Mohamadi,Thierry G. Vancaillie,Alan Lam,Nadia Willison,Jett Zivkovic,Richard J. Woodman,Monika Skubisz +8 more
- 11 Jan 2019
- Vol. 1, pp 100004-100004
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TL;DR: This study suggests that fractional CO2 laser is a safe, feasible, and beneficial treatment for SUI and may have a role as a minimally-invasive alternative to surgical management.
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Abstract: Objectives: To evaluate the impact of trans-vaginal fractional CO2 laser treatment on symptoms of stress urinary incontinence (SUI) in women. Study design: Women clinically diagnosed with SUI preferring non-surgical treatment were recruited to the study. Fractional CO2 laser system (MonaLisa T, DEKA) treatments were administered trans-vaginally every 4-6 weeks for a total of three treatments. Response to treatment was assessed at baseline (T1), at 3 months after treatment completion (T2) and at 12-24-month follow-up (T3) using the Australian Pelvic Floor Questionnaire (APFQ). The primary outcome was changes in reported symptoms of SUI. Secondary outcomes assessed included bladder function, urgency, urge urinary incontinence (UUI), pad usage, impact of urinary incontinence on quality of life (QOL) and degree of bothersome bladder. Results: Fifty-eight women were recruited and received the study treatment protocol. Eighty-two percent of participants reported an improvement in symptoms of SUI at completion of treatment (mild to no SUI) (p = <0.01). Treatment effect waned slightly when assessed at follow-up. Nevertheless, 71% of participants reported ongoing improvement in SUI symptoms at 12-24 months (p < 0.01). All secondary outcome measures were improved after treatment compared to baseline. Conclusions: This study suggests that fractional CO2 laser is a safe, feasible, and beneficial treatment for SUI and may have a role as a minimally-invasive alternative to surgical management.
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Citations
A validated self-administered female pelvic floor questionnaire
Kaven Baessler,Sheila O'Neill,Christopher G. Maher,Diana Battistutta +3 more
- 01 Jan 2010
TL;DR: This self-administered pelvic floor questionnaire assessed pelvic floor function in a reproducible and valid fashion and due to its responsiveness, can be used for routine clinical assessment and outcome research.
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Comparison of topical fractional CO2 laser and vaginal estrogen for the treatment of genitourinary syndrome in postmenopausal women: a randomized controlled trial.
Paula Fernanda Santos Pallone Dutra,Thais Heinke,Stella Catunda Pinho,Gustavo Rubino de Azevedo Focchi,Fernanda Kesselring Tso,Bruna Cristine de Almeida,Ivaldo Silva,Neila Maria de Góis Speck +7 more
TL;DR: The data suggest that laser therapy is an effective method for the treatment of vulvovaginal atrophy, despite the nonequivalence with topical estrogen therapy.
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Laser therapy for urinary incontinence and pelvic organ prolapse: a systematic review.
TL;DR: Laser therapy is now being proposed for the treatment of pelvic organ prolapse (POP) and urinary incontinence (UI) and it is being proposed that laser therapy should be used in addition to conventional surgery for these conditions.
28
The evidence behind the use of LASER for genitourinary syndrome of menopause, vulvovaginal atrophy, urinary incontinence and lichen sclerosus: A state‐of‐the‐art review
TL;DR: The effect of vaginal and vulvar LASER decreases with higher study quality where potential biases have been eliminated, and it is stressed that all patients who are treated with vaginal or vulvarLASER should be carefully monitored.
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CO2 Surgical Laser for Treatment of Stress Urinary Incontinence in Women: A Randomized Controlled Trial.
James Wood Alexander,Päivi K. Karjalainen,Lin Li Ow,Mugdha Kulkarni,Joseph C. Lee,Teemu Karjalainen,Alison Leitch,Germana Ryan,Anna Rosamilia +8 more
TL;DR: In this article , the effects of CO2 vaginal laser vs sham therapy for treating stress urinary incontinence were compared in a randomized controlled trial performed in outpatient clinics in two hospitals.
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References
Mid-urethral sling operations for stress urinary incontinence in women.
TL;DR: There is moderate quality evidence that in the short term (up to one year) the rate of subjective cure of TOR and RPR are similar, but subjective cure was similar between the groups, and overall rates of groin pain were higher in the TOR group than in the RPR group.
Updated Systematic Review and Meta-analysis of the Comparative Data on Colposuspensions, Pubovaginal Slings, and Midurethral Tapes in the Surgical Treatment of Female Stress Urinary Incontinence
Giacomo Novara,Walter Artibani,Matthew D. Barber,Christopher R. Chapple,Elisabetta Costantini,Vincenzo Ficarra,Paul Hilton,Carl Gustaf Nilsson,David Waltregny +8 more
TL;DR: In this paper, the authors evaluated the efficacy, complication, and reoperation rates of midurethral tapes compared with other surgical treatments for female SUI, and found that patients treated with RT experienced slightly higher continence rates than those treated with Burch colposuspension, but they faced a much higher risk of intraoperative complications.
488
Urinary Incontinence in Women: A Review
TL;DR: Clinicians should prioritize urinary incontinence detection, identify and treat modifiable factors, incorporate patient preference into evaluation and treatment, initiate conservative and medical therapy, and refer to specialists when underlying pathology is identified or conservative measures are ineffective.
452
A 12-week treatment with fractional CO2 laser for vulvovaginal atrophy: a pilot study.
Stefano Salvatore,Rossella E. Nappi,Nicola Zerbinati,Alberto Calligaro,Simone Ferrero,Massimo Origoni,Massimo Candiani,U. Leone Roberti Maggiore +7 more
TL;DR: A 12-week treatment with the fractional CO2 laser was feasible and induced a significant improvement of VVA symptoms by ameliorating vaginal health in postmenopausal women.
Microscopic and ultrastructural modifications of postmenopausal atrophic vaginal mucosa after fractional carbon dioxide laser treatment
Nicola Zerbinati,Maurizio Serati,Massimo Origoni,Massimo Candiani,Tommaso Iannitti,Stefano Salvatore,Francesco Marotta,Alberto Calligaro +7 more
TL;DR: The morphological findings support the effectiveness of fractional CO2 laser application for the restoration of vaginal mucosa structure and related physiological trophism and are clearly coupled with striking clinical relief from symptoms suffered by the patients before treatment.