Journal Article10.1002/JSFA.1873
Ferulic acid: pharmaceutical functions, preparation and applications in foods
Shiyi Ou,Kin-Chor Kwok +1 more
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TL;DR: Ferulic acid is a phenolic acid of low toxicity; it can be absorbed and easily metabolized in the human body and is used as the raw material for the production of vanillin and preservatives, as a cross-linking agent for the preparation of food gels and edible films, and as an ingredient in sports foods and skin protection agents.
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Abstract: Ferulic acid (4-hydroxy-3-methoxycinnamic acid), an effective component of Chinese medicine herbs such as Angelica sinensis, Cimicifuga heracleifolia and Lignsticum chuangxiong, is a ubiquitous phenolic acid in the plant kingdom. It is mainly conjugated with mono- and oligosaccharides, polyamines, lipids and polysaccharides and seldom occurs in a free state in plants. Ferulic acid is a phenolic acid of low toxicity; it can be absorbed and easily metabolized in the human body. Ferulic acid has been reported to have many physiological functions, including antioxidant, antimicrobial, anti-inflammatory, anti-thrombosis, and anti-cancer activities. It also protects against coronary disease, lowers cholesterol and increases sperm viability. Because of these properties and its low toxicity, ferulic acid is now widely used in the food and cosmetic industries. It is used as the raw material for the production of vanillin and preservatives, as a cross-linking agent for the preparation of food gels and edible films, and as an ingredient in sports foods and skin protection agents. Ferulic acid can be prepared by chemical synthesis and through biological transformation. As polysaccharide ferulate is a natural and abundant source of ferulic acid, preparation of ferulic acid from plant cell wall materials will be a prospective pathway.
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Citations
Free ferulic acid uptake in ram lambs.
TL;DR: In vitro analysis was conducted to assess the degree of inhibition of microbial NDF digestion caused by FA supplementation, and data in combination with the results of the lamb study indicate that free FA as 0.70% of DMI in lambs is absorbed and excreted in the urine as opposed to the feces with no apparent effects on rumen microbial N DF digestion.
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Variation of phenolic acids from herb and roots of Salsola kali L.
TL;DR: In this paper, qualitative and quantitative analysis of phenolic acids present as free and liberated from their conjunction with sugars and alcohols after hydrolysis in Salsola kali L was done, together with comparison of their content in roots and herb.
Pre-treatment of ferulic acid esterases immobilized on MNPs to enhance the extraction of ferulic acid from defatted rice bran in presence of ultrasound
TL;DR: In this paper, an ultrasound assisted enzymatic pre-treatment method was established to improve the yield of hydraulic acid (FA) extraction, which is a tough task due to its linkage with the hemicellulose.
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Attenuation of age-related changes in FOXO3a activity and the PI3K/Akt pathway by short-term feeding of ferulate
Yeon Ja Choi,Dae Hyun Kim,Eun Kyeong Lee,Ji Min Kim,Young Mi Ha,Nam Deuk Kim,Jee H. Jung,Jae Sue Choi,Byung Pal Yu,Hae Young Chung +9 more
TL;DR: The finding that short-term feeding of ferulate effectively modulates age-related renal FOXO3a, PI3K/Akt and insulin signaling pathways, and MnSOD and catalase expression, all of which may be beneficial for attenuating the aging process is found.
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Heteropolysaccharide preparations from rye and wheat bran as sources of antioxidants
TL;DR: In this paper, the antioxidant potential of heteropolysaccharides (HPS) isolated from several types of rye and wheat bran differing in terms of granularity (FG - fine granularity, CG - coarse granularity and WM - wholegrain) was determined.
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