Journal Article10.1002/JSFA.1873
Ferulic acid: pharmaceutical functions, preparation and applications in foods
Shiyi Ou,Kin-Chor Kwok +1 more
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TL;DR: Ferulic acid is a phenolic acid of low toxicity; it can be absorbed and easily metabolized in the human body and is used as the raw material for the production of vanillin and preservatives, as a cross-linking agent for the preparation of food gels and edible films, and as an ingredient in sports foods and skin protection agents.
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Abstract: Ferulic acid (4-hydroxy-3-methoxycinnamic acid), an effective component of Chinese medicine herbs such as Angelica sinensis, Cimicifuga heracleifolia and Lignsticum chuangxiong, is a ubiquitous phenolic acid in the plant kingdom. It is mainly conjugated with mono- and oligosaccharides, polyamines, lipids and polysaccharides and seldom occurs in a free state in plants. Ferulic acid is a phenolic acid of low toxicity; it can be absorbed and easily metabolized in the human body. Ferulic acid has been reported to have many physiological functions, including antioxidant, antimicrobial, anti-inflammatory, anti-thrombosis, and anti-cancer activities. It also protects against coronary disease, lowers cholesterol and increases sperm viability. Because of these properties and its low toxicity, ferulic acid is now widely used in the food and cosmetic industries. It is used as the raw material for the production of vanillin and preservatives, as a cross-linking agent for the preparation of food gels and edible films, and as an ingredient in sports foods and skin protection agents. Ferulic acid can be prepared by chemical synthesis and through biological transformation. As polysaccharide ferulate is a natural and abundant source of ferulic acid, preparation of ferulic acid from plant cell wall materials will be a prospective pathway.
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Citations
Production of natural value-added compounds: an insight into the eugenol biotransformation pathway
TL;DR: The present review focuses on eugenol biotransformation by microorganisms resulting in the formation of various value-added products such as ferulic acid, coniferyl alcohol, vanillin and vanillic acid.
51
Synthesis and antiviral activity of novel myricetin derivatives containing ferulic acid amide scaffolds
TL;DR: Results suggested that novel myricetin derivatives bearing ferulic acid amide scaffolds may be considered as an activator for antiviral agents.
51
Biomedical applications of ferulic acid encapsulated electrospun nanofibers
TL;DR: Investigating the shortcomings associated with agro-waste derived ferulic acid by encapsulating it in electrospun nanofibrous matrix of poly (d,l-lactide-co-glycolide)/polyethylene oxide found that it resides in the core of PLGA/PEO nan ofibers, which could be potentially explored for therapeutic usage in biomedical sector.
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Anti-inflammatory activity and phenolic composition of prickly pear (Opuntia ficus-indica) flowers
Imène Ammar,Maryem Ben Salem,Bahira Harrabi,Massara Mzid,Sana Bardaa,Zouheir Sahnoun,Hamadi Attia,Monia Ennouri +7 more
TL;DR: In this article, the in vivo anti-inflammatory activity of methanolic extract of Prickly pear Opuntia ficus-indica flowers was studied using carrageenan induced rat paw edema model.
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The structure-antioxidant activity relationship of dehydrodiferulates.
Yuan Jia,Ying He,Fachuang Lu +2 more
TL;DR: Comparing the antioxidant activities of the tested diferulates suggested that the phenolic hydroxyl group, electron donating methoxylgroup, and stable conjugated transient structures dictate the antioxidant activity of diferulate.
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TL;DR: By virtue of effectively scavenging deleterious radicals and suppressing radiation-induced oxidative reactions, ferulic acid may serve an important antioxidant function in preserving physiological integrity of cells exposed to both air and impinging UV radiation.
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