Journal Article10.1002/JSFA.1873
Ferulic acid: pharmaceutical functions, preparation and applications in foods
Shiyi Ou,Kin-Chor Kwok +1 more
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TL;DR: Ferulic acid is a phenolic acid of low toxicity; it can be absorbed and easily metabolized in the human body and is used as the raw material for the production of vanillin and preservatives, as a cross-linking agent for the preparation of food gels and edible films, and as an ingredient in sports foods and skin protection agents.
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Abstract: Ferulic acid (4-hydroxy-3-methoxycinnamic acid), an effective component of Chinese medicine herbs such as Angelica sinensis, Cimicifuga heracleifolia and Lignsticum chuangxiong, is a ubiquitous phenolic acid in the plant kingdom. It is mainly conjugated with mono- and oligosaccharides, polyamines, lipids and polysaccharides and seldom occurs in a free state in plants. Ferulic acid is a phenolic acid of low toxicity; it can be absorbed and easily metabolized in the human body. Ferulic acid has been reported to have many physiological functions, including antioxidant, antimicrobial, anti-inflammatory, anti-thrombosis, and anti-cancer activities. It also protects against coronary disease, lowers cholesterol and increases sperm viability. Because of these properties and its low toxicity, ferulic acid is now widely used in the food and cosmetic industries. It is used as the raw material for the production of vanillin and preservatives, as a cross-linking agent for the preparation of food gels and edible films, and as an ingredient in sports foods and skin protection agents. Ferulic acid can be prepared by chemical synthesis and through biological transformation. As polysaccharide ferulate is a natural and abundant source of ferulic acid, preparation of ferulic acid from plant cell wall materials will be a prospective pathway.
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Citations
Anti-fungal activity of phenolic sweet orange peel extract for controlling fungi responsible for post-harvest fruit decay.
Alejandro Hernández,Santiago Ruiz-Moyano,Ana Isabel Galván,Almudena V. Merchán,Francisco Pérez Nevado,Emilio Aranda,Manuel Joaquín Serradilla,María de Guía Córdoba,Alberto Martín +8 more
TL;DR: Results highlight peel orange waste as an excellent source of anti-fungal compounds, suggesting the possibility of using ferulic acid or ferulic Acid-rich extracts, either alone or in combination with other post-harvest treatment, as a natural alternative to reduce post-Harvest losses and, also, enhance the shelf-life of fruit.
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Multifunctional alkyl ferulate esters as potential food additives: Antibacterial activity and mode of action against Listeria monocytogenes and its application on American sturgeon caviar preservation
Shi Yugang,Bian Liqing,Yun-Jie Zhu,Run-run Zhang,Shi-Yin Shao,Wu Yu,Yue-wen Chen,Yali Dang,Yue Ding,Hao Sun +9 more
TL;DR: The effectiveness of FAC6 against L. monocytogenes is highlighted, suggesting that FAC6 with both antioxidant and antibacterial activities can be used as an effective and safe multifunctional food additive for American (Amer) sturgeon caviar preservation.
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Nelumbo nucifera leaves protect hydrogen peroxide-induced hepatic damage via antioxidant enzymes and HO-1/Nrf2 activation
Jae-Young Je,Da-Bin Lee +1 more
TL;DR: The phenolic composition and hepatoprotective effect of the butanolic extract (BE) from Nelumbo nucifera leaves against H2O2-induced hepatic damage in cultured hepatocytes were investigated and BE up-regulated intracellular glutathione levels under normal and oxidative stress conditions.
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Simultaneous quantification of active components in the herbs and products of Si-Wu-Tang by high performance liquid chromatography-mass spectrometry.
Zhijun Wang,Siukwan Wo,Ling Wang,Ling Wang,Clara Bik-San Lau,Vincent H.L. Lee,Moses S. S. Chow,Moses S. S. Chow,Zhong Zuo +8 more
TL;DR: A high performance liquid chromatography-mass spectrometric method employing both positive and negative electrospray ionization was developed for the simultaneous determination of the nine identified compounds in the raw herbs and products of Si-Wu-Tang.
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Systems pharmacology to decipher the combinational anti-migraine effects of Tianshu formula
Yan Li,Jingxiao Zhang,Lilei Zhang,Xuetong Chen,Yanqiu Pan,Su-Shing Chen,Shuwei Zhang,Zhenzhong Wang,Wei Xiao,Ling Yang,Yonghua Wang +10 more
TL;DR: A novel systems pharmacology-based method which integrates pharmacokinetic filtering, target fishing and network analysis was developed and exemplified by a probe, i.e. Tianshu formula, a widely clinically used anti-migraine herbal formula in China which comprises of Rhizoma chuanxiong and Gastrodia elata.
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