Journal Article10.1002/JSFA.1873
Ferulic acid: pharmaceutical functions, preparation and applications in foods
Shiyi Ou,Kin-Chor Kwok +1 more
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TL;DR: Ferulic acid is a phenolic acid of low toxicity; it can be absorbed and easily metabolized in the human body and is used as the raw material for the production of vanillin and preservatives, as a cross-linking agent for the preparation of food gels and edible films, and as an ingredient in sports foods and skin protection agents.
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Abstract: Ferulic acid (4-hydroxy-3-methoxycinnamic acid), an effective component of Chinese medicine herbs such as Angelica sinensis, Cimicifuga heracleifolia and Lignsticum chuangxiong, is a ubiquitous phenolic acid in the plant kingdom. It is mainly conjugated with mono- and oligosaccharides, polyamines, lipids and polysaccharides and seldom occurs in a free state in plants. Ferulic acid is a phenolic acid of low toxicity; it can be absorbed and easily metabolized in the human body. Ferulic acid has been reported to have many physiological functions, including antioxidant, antimicrobial, anti-inflammatory, anti-thrombosis, and anti-cancer activities. It also protects against coronary disease, lowers cholesterol and increases sperm viability. Because of these properties and its low toxicity, ferulic acid is now widely used in the food and cosmetic industries. It is used as the raw material for the production of vanillin and preservatives, as a cross-linking agent for the preparation of food gels and edible films, and as an ingredient in sports foods and skin protection agents. Ferulic acid can be prepared by chemical synthesis and through biological transformation. As polysaccharide ferulate is a natural and abundant source of ferulic acid, preparation of ferulic acid from plant cell wall materials will be a prospective pathway.
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Citations
Preparation and property studies of chitosan-PVA biodegradable antibacterial multilayer films doped with Cu2O and nano-chitosan composites
TL;DR: In this paper, the multilayer films containing chitosan and polyvinyl alcohol were prepared by Layer-by-Layer assembly technology with the addition of ferulic acid as a cross-linking agent.
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Feruloylated Oligosaccharides from Maize Bran Modulated the Gut Microbiota in Rats
Juanying Ou,Junqing Huang,Yuan Song,Sheng-wen Yao,Xichun Peng,Mingfu Wang,Mingfu Wang,Shiyi Ou +7 more
TL;DR: Oral administration of feruloylated oligosaccharides from maize bran greatly increased the reads of bacteria that were previously found resistant against diabetes in rats, such as Actinobacteria, Bacteroides, and Lactobacillus; whereas decreased diabetes-prone bacteria,such as Clostridium and Firmicutes.
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Expression, characterization and structural modelling of a feruloyl esterase from the thermophilic fungus Myceliophthora thermophila
TL;DR: Ferulic acid (FA) was efficiently released from destarched wheat bran when the esterase was incubated together with an M3 xylanase from Trichoderma longibrachiatum (a maximum of 41% total FA released after 1 h incubation) and prediction of the secondary structure of MtFae1a was performed in the PSIPRED server whilst modelling the 3D structure was accomplished by the use of the HH3D structure prediction server.
69
Ferulic acid production from brewery spent grains, an agro-industrial waste
TL;DR: In this article, the authors used X-ray diffraction analysis of the raw and hydrolyzed brewery spent grains (BSG) for the extraction of a natural antioxidant, the ferulic acid.
67
Maximizing the Efficiency of Vanillin Production by Biocatalyst Enhancement and Process Optimization.
TL;DR: These findings showed that recombinant plasmid-free E. coli strains are promising candidates for the production of vanillin at industrial scale and that a reduction of the cost of the bioconversion process requires approaches that minimize the toxicity of both ferulic acid and vanillin.
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