Journal Article10.1016/S0140-6736(04)15794-2
Fatigue in neurological disorders
Abhijit Chaudhuri,Peter O. Behan +1 more
TL;DR: A state of pre-existing relative hypocortisolaemia might sensitise the hypothalamic-pituitary-adrenal axis to development of persistent central fatigue after stress.
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About: This article is published in The Lancet. The article was published on 20 Mar 2004. The article focuses on the topics: Chronic fatigue & Chronic fatigue syndrome.
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Citations
Fatigue in Multiple Sclerosis: General and Perceived Fatigue Does Not Depend on Corticospinal Tract Dysfunction
Laura Mordillo-Mateos,Vanesa Soto-León,Marta Torres-Pareja,Diego Peinado-Palomino,Nuria Mendoza-Laiz,Carlos Alonso-Bonilla,Michele Dileone,Mario Rotondi,Juan Aguilar,Antonio Oliviero +9 more
TL;DR: In MS patients the pathogenesis of fatigue seems not driven by the mechanisms directly related to corticospinal function (that characterize fatigue in controls) but seems probably due to other “central abnormalities” upstream to primary motor cortex.
Kindling and Oxidative Stress as Contributors to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Leonard A. Jason,Nicole Porter,Joshua Herrington,Matthew Sorenson,Stan Kubow +4 more
- 01 Jan 2009
TL;DR: It is proposed that the kindling and oxidative stress theories provide a heuristic template for better understanding the at times conflicting findings regarding the etiology and pathophysiology of this illness.
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Using Functional Magnetic Resonance Imaging to Detect Chronic Fatigue in Patients With Previous Traumatic Brain Injury: Changes Linked to Altered Striato-Thalamic-Cortical Functioning.
Nils Berginström,Peter Nordström,Urban Ekman,Johan G. Eriksson,Micael Andersson,Lars Nyberg,Anna Nordström +6 more
TL;DR: The results suggest that chronic fatigue after TBI is associated with altered striato-thalamic-cortical functioning, and fMRI scanning during performance of a fatiguing 27-minute attention task is used to detect fatigue.
29
Prevalence of fatigue and associated factors in chronic low back pain patients
Marina de Góes Salvetti,Cibele Andrucioli de Mattos Pimenta,Patrícia Emília Braga,Michael McGillion +3 more
TL;DR: In this paper, a cross-sectional study of 215 chronic low back pain patients from three health care centers and two industrial corporations was conducted to determine the prevalence and key factors associated with fatigue in CLL patients.
Fatigue in Parkinson's Disease.
TL;DR: There is an emerging science of fatigue which is based on a careful and precise taxonomy of the construct of fatigue, including definitions useful for both research and clinical care as discussed by the authors, and an overview for an approach to the assessment and management of persons with Parkinson's disease who complain of problematic fatigue.
29
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