Journal Article10.1016/J.YGYNO.2011.05.038
Factors associated with parametrial involvement in stage IB1 cervical cancer and identification of patients suitable for less radical surgery
Junichi Kodama,Tomoyuki Kusumoto,Keiichiro Nakamura,Noriko Seki,Atsushi Hongo,Yuji Hiramatsu +5 more
TL;DR: Elderly age, depth of invasion, tumor size, lymph vascular space invasion (LVSI), positive pelvic nodes, and ovarian metastasis were significantly associated with parametrial involvement, and LVSI, deep stromal invasion, and elderly age to be the independent predictors of parametri involvement.
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About: This article is published in Gynecologic Oncology. The article was published on 01 Sep 2011. The article focuses on the topics: Parametrial & Radical surgery.
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Citations
Early stage cervical cancer: role of magnetic resonance imaging after conization in determining residual tumor.
TL;DR: Identifiable tumor on MRI after conization in patients with early stage cervical cancer was an independent predictor of residual tumor at final pathology.
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Factors associated with parametrial involvement in patients with stage IB1 cervical cancer: Who is suitable for less radical surgery?
TL;DR: It is suggested that tumor size may be a strong predictor of parametrial involvement in International Federation of Gynecology and Obstetrics stage IB1 cervical cancer, which can be used to select a subgroup population for less radical surgery.
Tailoring radicality in early cervical cancer: how far can we go?
TL;DR: In this paper, a case-control and retrospective case series suggest that trachelectomy is safe as long as the tumor diameter does not exceed 2 cm for cervical cancer patients.
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Pre-operative surgical algorithm: sentinel lymph node biopsy as predictor of parametrial involvement in early-stage cervical cancer
Vincent Balaya,Vincent Balaya,Arnaud Bresset,Benedetta Guani,Benedetta Guani,Louise Benoit,Laurent Magaud,H Bonsang-Kitzis,Charlotte Ngo,Patrice Mathevet,Patrice Mathevet,Fabrice Lecuru +11 more
TL;DR: Less radical surgery may be an option for patients with bilateral negative SLN after ultrastaging and tumors <20 mm and sentinel lymph node (SLN) status should be integrated into the decision-making process for tailored surgery in early-stage cervical cancer.
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[The 2019 FIGO classification for cervical carcinoma-what's new?]
TL;DR: Das mikroinvasive Karzinom wird allein durch die Tiefe der Stromainfiltration definiert, die flächige (horizontale) Ausdehnung ist nunmehr irrelevant.
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References
Class II versus class III radical hysterectomy in stage IB-IIA cervical cancer: a prospective randomized study.
Fabio Landoni,Andrea Maneo,Gennaro Cormio,T. Patrizia Perego,Rodolfo Milani,Orlando Caruso,Costantino Mangioni +6 more
TL;DR: The data confirm the need of tailoring the extent of resection to the characteristics of the cervical neoplasia and open new interesting pathways to upcoming protocols for the conservative management of these tumors.
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Utility of parametrectomy for early stage cervical cancer treated with radical hysterectomy.
Jason D. Wright,Perry W. Grigsby,Rebecca A. Brooks,Matthew A. Powell,Randall K. Gibb,Feng Gao,Janet S. Rader,David G. Mutch +7 more
TL;DR: The objective of the study was to determine factors predictive of parametrial tumor spread and to define a subset of patients at low risk forParametrial disease.
196
Nerve-sparing and individually tailored surgery for cervical cancer
TL;DR: This Review focuses on the neuroanatomy of the pelvis and the possible damage of autonomic nerves, and suggests options for the sparing of these nerves during surgery for cervical cancer.
122
A prospective study of sentinel lymph node status and parametrial involvement in patients with small tumour volume cervical cancer.
TL;DR: No PI was observed in early cervical cancer if SLNs were negative, however, the authors found PI in 28.0% of women with positive SLN and radical removal of parametrium in SLN negative patients is questionable.
82
Frequency of Pelvic Lymph Node Metastases and Parametrial Involvement in Stage IA2 Cervical Cancer: A Population-Based Study and Literature Review
TL;DR: In patients with stage IA2 squamous cell cancer with lymph vascular space invasion, a standard pelvic lymph node dissection should be recommended andParametrectomy should be included if the nodes are positive.
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