Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease

TL;DR: In this article , the evidence of diabetic choroidopathy in vivo was confirmed with multimodal imaging, which provides key quantitative and qualitative features to characterize the choroidal involvement.

TL;DR: Wang et al. as mentioned in this paper developed an in situ verteporfin delivery system with a photoswitching synergistic function that disassembles in response to intraocular inflammatory enzymes, which provides a promising strategy with synergistic antiangiogenic effects for the treatment of choroidal vascular diseases.

TL;DR: In this paper , the peripapillary flow deficit percentage (CC FD), vessel density (VD), and perfusion density (PD) were quantified to determine the predictive value of the microcirculation of the optic nerve head by OCT angiography for identifying individuals with high risk of diabetic retinopathy (DR) progression and diabetic macular edema (DME) development.

TL;DR: Outside retinal and choroidal parameters were quantified to understand better the pathogenesis of diabetic retinopathy and diabetic macular edema and other pathogenic mechanisms seem to predominate in the latter group.

TL;DR: Infrared imaging delineates intratumoral vessels in choroidal tumors appearing as dark beaded loops and tufts in CCH, and vascular loops on IR imaging showed a high diagnostic sensitivity for CCH.

TL;DR: A full understanding of how complement regulation is compartmentalized in the eye is required is required, a topic that will be highlighted in this review.

TL;DR: This study indicates that cCSC is a progressive disease in many patients, causing a progressive decline in visual acuity, accompanied by lower reported vision-related quality of life.

TL;DR: The objective of this study was to characterize NG2 expression along vessels within rat microvascular networks and compare this to SM α‐actin expression.