Exercise as medicine – evidence for prescribing exercise as therapy in 26 different chronic diseases
TL;DR: This review provides the reader with the up‐to‐date evidence‐based basis for prescribing exercise as medicine in the treatment of 26 different diseases: psychiatric diseases (depression, anxiety, stress, schizophrenia).
read more
Abstract: This review provides the reader with the up-to-date evidence-based basis for prescribing exercise as medicine in the treatment of 26 different diseases: psychiatric diseases (depression, anxiety, stress, schizophrenia); neurological diseases (dementia, Parkinson's disease, multiple sclerosis); metabolic diseases (obesity, hyperlipidemia, metabolic syndrome, polycystic ovarian syndrome, type 2 diabetes, type 1 diabetes); cardiovascular diseases (hypertension, coronary heart disease, heart failure, cerebral apoplexy, and claudication intermittent); pulmonary diseases (chronic obstructive pulmonary disease, asthma, cystic fibrosis); musculo-skeletal disorders (osteoarthritis, osteoporosis, back pain, rheumatoid arthritis); and cancer. The effect of exercise therapy on disease pathogenesis and symptoms are given and the possible mechanisms of action are discussed. We have interpreted the scientific literature and for each disease, we provide the reader with our best advice regarding the optimal type and dose for prescription of exercise.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Energy System Assessment in Survivors of Breast Cancer.
Antonio Cuesta-Vargas,Antonio Cuesta-Vargas,Jena Buchan,Bella Pajares,Emilio Alba,Manuel Trinidad-Fernández,Sofia Ruiz-Medina,José Manuel García-Almeida,María José Ríos-López,Cristina Roldán-Jiménez +9 more
TL;DR: Using a combination of HR and RPE, as well as baseline assessment of each energy system, clinicians may improve ability to prescribe personalized exercise and give patients greater ability to self-monitor intensity and progress.
12
Low-Intensity Exercise as a Modifier of Depressive Symptoms and Self-Perceived Stress Level in Women with Metabolic Syndrome.
Paulina Morga,Błażej Cieślik,Małgorzata Sekułowicz,Maria Magdalena Bujnowska-Fedak,Iris Sharon Drower,Joanna Szczepańska-Gieracha +5 more
TL;DR: It is suggested that low-intensity exercise combined with psychoeducation could lower depressive symptoms and stress level in women with metabolic syndrome, however, the intervention does not lower anthropometric parameter scores.
Endurance Exercise-Induced Fgf21 Promotes Skeletal Muscle Fiber Conversion through TGF-β1 and p38 MAPK Signaling Pathway
TL;DR: In this paper , the authors investigated the role of Fgf21 in skeletal muscle fiber conversion in response to endurance training and found that it promoted the markers of fiber-type transition and eMyHC-positive myotubes by inhibiting the TGFβ1 signaling axis and activating the p38 MAPK pathway without apparent crosstalk.
12
A Physiological Profile of Ovarian Cancer Survivors to Inform Tailored Exercise Interventions and the Development of Exercise Oncology Guidelines.
Christelle Schofield,Robert U. Newton,Daniel A. Galvão,Paul A. Cohen,Carolyn J. Peddle-McIntyre +4 more
TL;DR: It is suggested that ovarian cancer survivors could benefit from physical activity and exercise oncology interventions aimed at addressing detrimental changes to physiological status due to disease and treatment.
12
Pediatric Sports-Related Concussion: An Approach to Care:
Olivia E. Podolak,Kristy B. Arbogast,Kristy B. Arbogast,Christina L. Master,Christina L. Master,David A. Sleet,Matthew F. Grady,Matthew F. Grady +7 more
TL;DR: This data indicates that concussions in children and adolescents aged under the age of 16 are more likely to be associated with head injury than with other sports injuries.
12
References
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.
William C. Knowler,Elizabeth Barrett-Connor,Sarah E. Fowler,Richard F. Hamman,John M. Lachin,Elizabeth A. Walker,David M. Nathan +6 more
TL;DR: In this paper, the authors compared a lifestyle intervention with metformin to prevent or delay the development of Type 2 diabetes in nondiabetic individuals. And they found that the lifestyle intervention was significantly more effective than the medication.
19.4K
Global Prevalence of Diabetes: Estimates for the year 2000 and projections for 2030
TL;DR: Findings indicate that the "diabetes epidemic" will continue even if levels of obesity remain constant, and given the increasing prevalence of obesity, it is likely that these figures provide an underestimate of future diabetes prevalence.
18.4K
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance.
Jaakko Tuomilehto,Jon Lindstrom,Johan G. Eriksson,Valle Tt,Helena Hämäläinen,Pirjo Ilanne-Parikka,Keinänen-Kiukaanniemi S,Mauri Laakso,Anne Louheranta,Rastas M,Salminen,Matti Uusitupa +11 more
TL;DR: Type 2 diabetes can be prevented by changes in the lifestyles of high-risk subjects by means of individualized counseling aimed at reducing weight, total intake of fat, and intake of saturated fat and increasing intake of fiber and physical activity.
11.4K
Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies.
TL;DR: Throughout middle and old age, usual blood pressure is strongly and directly related to vascular (and overall) mortality, without any evidence of a threshold down to at least 115/75 mm Hg.
10.5K