Evolutionary biology of aging

TL;DR: It is found that LH selection resulted in the evolution of age-specific reproduction and mortality but these changes were largely unaffected by sexual selection, supporting the hypothesis that sex differences in LH—a historical signature of sexual selection—are key in shaping trait responses to novel selection.

TL;DR: The key endocrinological mediators of life history trade-offs, particularly those involving reproduction, are emphasized.

TL;DR: Analysis of body weight of domestic sheep lambs demonstrates that onset of reproductive senescence in ewes occurs already at 5 and 6 years of age when measured, respectively, as lamb weight and litter size produced, and hypothesize that there may be a cost of selection for large litter size in mammalian herbivores.

TL;DR: In this paper, the relevance of population structure and reproductive value as key to understanding selection gradients, and therefore senescence, is discussed, and four key aspects can help us understand why patterns of negligible and negative senescences can actually be explained under the same evolutionary framework as classical senescentence.