Journal Article10.5694/J.1326-5377.2001.TB143069.X
Ethics and evidence-based medicine
164
TL;DR: Ongoing debate about the ethics of EBM on all levels will ensure that EBM manifests intended and preferred social values and takes its rightful place in the practice of medicine and the development of health policy.
read more
Abstract: Concerns about the ethics of evidence-based medicine (EBM) relate to possible alterations in the humane basis of clinical care. In collecting the evidence for EBM, scientists and doctors, not consumers, determine research objectives, interpret the data and implement the findings, and in doing so may disregard patients' priorities. Ethical standards, and what counts as evidence, are determined by socially or commercially powerful groups connected to powerful institutions. Such groups can generate evidence and determine "gold standard" knowledge, filtering out other, "inferior" knowledge. Applying the available evidence to predicting outcomes for individual patients involves uncertainty. Full disclosure of this uncertainty is a component of informed consent, but requires sensitivity to patients' tolerance of ambiguity. Ongoing debate about the ethics of EBM on all levels will ensure that EBM manifests intended and preferred social values and takes its rightful place in the practice of medicine and the development of health policy.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Connecting pre-marketing clinical research and medical practice. The case of the cardiovascular drugs
Nicoline Wieringa
- 01 Jan 2001
TL;DR: There is a need to focus regulatory standards more on the needs in medical practice, and regulatory authorities should further develop their influence in the pre- and post-marketing drug development process, together with other parties involved, in order to bridge the gap between clinical research and medical practice.
Moving evidence-based interventions to populations: a case study using social workers in primary care
Scott Miyake Geron,Bronwyn Keefe +1 more
TL;DR: A randomized controlled trial is employed to test the effectiveness of a social work intervention for frail older adults that uses PST to address depression and other psychosocial issues.
9
Ethical considerations in the globalization of medicine – an interview with James Giordano
TL;DR: Some of the most important ethical problems that should be considered when conducting biomedical research in all types of clinical settings are discussed, with particular emphasis on some of the main challenges of research in low-and-middle-income countries.
Evidence-based healthcare 10 years on: is the National Institute of Clinical Studies the answer?
Louise V Hall,Allison E Lauder +1 more
TL;DR: It is imperative that NICS include a consumer on its Board, as the relevance and acceptability of quality initiatives undertaken by NICS will have an impact on health outcomes for consumers, and it is important that such initiatives take into account the preferences of consumers.
9
References
•Book
Power/Knowledge: Selected Interviews and Other Writings 1972-1977
Michel Foucault,Colin Gordon +1 more
- 01 Jan 1980
TL;DR: The Eye of Power: A Discussion with Maoists as mentioned in this paper discusses the politics of health in the Eighteenth Century, the history of sexuality, and the Confession of the Flesh.
22.2K
Evidence based medicine: what it is and what it isn't.
TL;DR: Evidence Based Medicine (IBM) as discussed by the authors is the conscientious, explicit, and judicious use of current best evidence in making decisions about the care of individual patients, which is a hot topic for clinicians, public health practitioners, purchasers, planners and the public.
Statistical Power, Sample Size, and Their Reporting in Randomized Controlled Trials
TL;DR: The pattern over time in the level of statistical power and the reporting of sample size calculations in published randomized controlled trials (RCTs) with negative results is described and few trials discussed whether the observed differences were clinically important.
599
Clinical Epidemiology: A Basic Science for Clinical Medicine
TL;DR: Clinical Epidemiology is a book dedicated to "H.L. Mencken, Kurt Vonnegut, Jr., Douglas Adams, and the Emperor's New Clothes" and offers clear and practical explanations for an array of epidemiologic concepts ranging from sensitivity and specificity to "zero-time shift" and "inception".
550
Cholesterol lowering and mortality: the importance of considering initial level of risk.
TL;DR: Currently evaluated cholesterol lowering drugs seem to produce mortality benefits in only a small proportion of patients at very high risk of death from coronary heart disease, and future trials should aim to clarify the level of risk above which treatment is of net benefit.
420