Estimation of toxic hazard—A decision tree approach

doi:10.1016/S0015-6264(76)80522-6

Journal Article10.1016/S0015-6264(76)80522-6

Estimation of toxic hazard—A decision tree approach

G.M. Cramer, +2 more

- 01 Jan 1976

- Food and Cosmetics Toxicology

- Vol. 16, Iss: 3, pp 255-276

1.3K

TL;DR: A procedure for making a significant part of this process rational, public and explicit is proposed, which consists of a ‘decision tree’ of 33 questions, each answered ‘yes’ or ‘no’, and rests heavily on known data on metabolism and toxicity.

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References

•Book

Registry of Toxic Effects of Chemical Substances

Richard J. Lewis, +1 more

- 01 Nov 1986

1K

Journal Article•10.1016/S0015-6264(77)80014-X

Criteria employed by the expert panel of FEMA for the GRAS evaluation of flavouring substances.

B.L. Oser, +1 more

- 01 Jan 1977

- Food and Cosmetics Toxicology

TL;DR: An updated account is presented of the activities or the Expert Panel of the Flavor and Extract Manufacturers' Association for establishing the generally recognized as safe (GRAS) status of flavouring substances in accordance with the Food Additives Amendment to the US Federal Food, Drug, and Cosmetic Act.

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