Journal Article10.1016/S0015-6264(76)80522-6
Estimation of toxic hazard—A decision tree approach
G.M. Cramer,R.A. Ford,R.L. Hall +2 more
1.3K
TL;DR: A procedure for making a significant part of this process rational, public and explicit is proposed, which consists of a ‘decision tree’ of 33 questions, each answered ‘yes’ or ‘no’, and rests heavily on known data on metabolism and toxicity.
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About: This article is published in Food and Cosmetics Toxicology. The article was published on 01 Jan 1976.
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Citations
Derivation of Occupational Thresholds of Toxicological Concern for Systemically Acting Noncarcinogenic Organic Chemicals.
TL;DR: The proposed OTTCs are not meant to replace the traditional occupational exposure limits, but can be used in data-poor situations along with exposure estimates to support screening level risk assessment and prioritization.
14
Hazard assessment using an in-silico toxicity assessment of the transformation products of boscalid, pyraclostrobin, fenbuconazole and glyphosate generated by exposure to an advanced oxidative process.
TL;DR: Several transformation products of boscalid, pyraclostrobin and fenbuconazole should be strongly considered for further testing, either by quantifying their production or in- vivo and in-vitro toxicity tests due to their predicted toxicity and associated hazard.
14
Determining the Applicability of Threshold of Toxicological Concern Approaches to Substances Found in Foods
Richard Canady,Richard W. Lane,Greg Paoli,Margaret Wilson,Heidi Bialk,Steven Hermansky,Brent Kobielush,Ji-Eun Lee,Craig Llewellyn,Joseph Scimeca +9 more
TL;DR: Issues to be considered by risk managers when faced with the situation of an unexpected substance in food are described, demonstrating the steps taken in deciding whether it would be appropriate to apply the TTC approach in each case.
References
•Book
Registry of Toxic Effects of Chemical Substances
Richard J. Lewis,Rodger L. Tatken +1 more
- 01 Nov 1986
1K
Criteria employed by the expert panel of FEMA for the GRAS evaluation of flavouring substances.
B.L. Oser,R.L. Hall +1 more
TL;DR: An updated account is presented of the activities or the Expert Panel of the Flavor and Extract Manufacturers' Association for establishing the generally recognized as safe (GRAS) status of flavouring substances in accordance with the Food Additives Amendment to the US Federal Food, Drug, and Cosmetic Act.
48
•Book
Lists of volatile compounds in food.
S. van Straten,Flora de Vrijer,Centraal Instituut voor Voedingsondeizoek Tno +2 more
- 01 Jan 1973
19
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