Estimation of toxic hazard—A decision tree approach

TL;DR: A new framework for potential assessment of chronic toxicity made possible with the power of modern reliable databases and chemoinformatic methods is proposed.

TL;DR: In this article, the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States.

TL;DR: It can be concluded that the Cramer’s rule can be used for the parametrization of the UV absorbance data of phenol and its main intermediate products, and UV-visible spectroscopy can be selected instead of HPLC in much of the experiments concerning with aqueous-phase reactions.

TL;DR: In order to keep pace with the increased need for expanded analytical capability - faster throughput, more analytes per sample - chromatographic separation capability still needs to grow, and orthogonal separation techniques and multi-dimensional chromatography are key tools for the future.

TL;DR: An updated account is presented of the activities or the Expert Panel of the Flavor and Extract Manufacturers' Association for establishing the generally recognized as safe (GRAS) status of flavouring substances in accordance with the Food Additives Amendment to the US Federal Food, Drug, and Cosmetic Act.