Epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of COVID-19: a review of current evidence.
TL;DR: The COVID-19 pandemic has created a public health crisis, infected millions of people, and caused a significant number of deaths as mentioned in this paper, and SARS-CoV-2 transmits from person to person through several routes.
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Abstract: The COVID-19 pandemic has created a public health crisis, infected millions of people, and caused a significant number of deaths. SARS-CoV-2 transmits from person to person through several routes, ...
read more
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Citations
Omicron variant (B.1.1.529) and its sublineages: What do we know so far amid the emergence of recombinant variants of SARS-CoV-2?
Manish Dhawan,AbdulRahman A. Saied,Saikat Mitra,Fahad A. Alhumaydhi,Talha Bin Emran,Polrat Wilairatana +5 more
TL;DR: The Omicron variant has been identified as a highly modified, contagious, and crucial variant among the five VOCs of SARS-CoV-2 in the COVID-19 pandemic as mentioned in this paper .
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High COVID-19 Vaccine Hesitancy Among Healthcare Workers: Should Such a Trend Require Closer Attention by Policymakers?
TL;DR: A cross-sectional pilot survey was conducted using an online questionnaire between 13 and 25 January 2021 to examine the perceptions, attitudes, and acceptability of the COVID-19 vaccination among healthcare workers in India as discussed by the authors.
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Dual-Gene-Controlled Rolling Circle Amplification Strategy for SARS-CoV-2 Analysis
Ying Deng,Tianci Zhou,Ying Peng,Minghui Wang,Liangliang Xiang,Yuanyuan Zhang,Jinlong Li,Jie Yang,Genxi Li +8 more
TL;DR: Wang et al. as mentioned in this paper designed an ingenious dual-gene-controlled rolling circle amplification (RCA) strategy to detect SARS-CoV-2 in the range of 0.1-5000 pM, with the detection limit of 57 fM.
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Oral Lesions in Pediatric Subjects: SARS-CoV-2 Infection and COVID-19 Vaccination
Federica di Spirito,Mario Caggiano,Mariagiovanna Di Palo,Maria Contaldo,Francesco D’Ambrosio,Stefano Martina,Alessandra Amato +6 more
TL;DR: Assessment of the prevalence and macro-microscopic features of oral lesions following SARS-CoV-2 infection, grading primary oral lesions based on COVID-19 forms, in pediatric subjects found most of the rare lesions recorded were a part of broad-spectrum systemic disorders and syndromes.
Association between COVID-19 morbidity, mortality, and gross domestic product, overweight/ obesity, non-communicable diseases, vaccination rate: A cross-sectional study
Kuat Oshakbayev,Zulfiya Zhankalova,Meruyert Gazaliyeva,Khalit Mustafin,Gulnara Bedelbayeva,Bibazhar Dukenbayeva,Nurzhan Otarbayev,Attila Tordai +7 more
TL;DR: In this paper , the influence of country's gross domestic product, population prevalence of overweight/ obesity, NCD mortality, and vaccination on COVID-19 morbidity and mortality rates was studied.
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TL;DR: The receptor-binding domain (RBD) in SARS-CoV-2 S protein was identified and it was found that the RBD protein bound strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors and could block the binding and, hence, attachment of SARs-Cov-2 RBD and SARS -CoV RBD to ACE2-expressing cells, thus inhibiting their infection to host cells.
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Spike mutation D614G alters SARS-CoV-2 fitness.
Jessica A. Plante,Yang Liu,Jianying Liu,Hongjie Xia,Bryan A. Johnson,Kumari G. Lokugamage,Xianwen Zhang,Antonio E. Muruato,Jing Zou,Camila R. Fontes-Garfias,Divya Mirchandani,Dionna Scharton,John P. Bilello,Zhiqiang Ku,Zhiqiang An,Birte Kalveram,Alexander N. Freiberg,Vineet D. Menachery,Xuping Xie,Kenneth S. Plante,Scott C. Weaver,Pei Yong Shi +21 more
TL;DR: Hamsters infected with SARS-CoV-2 expressing spike D614G (G614 virus) produced higher infectious titres in nasal washes and the trachea, but not in the lungs, supporting clinical evidence showing that the mutation enhances viral loads in the upper respiratory tract of COVID-19 patients and may increase transmission.