Epidemiology and Risk Factors in Non-infectious Uveitis: A Systematic Review
TL;DR: In this paper, a systematic literature search of Pubmed/MEDLINE database was performed in the 50-year period from January 1971 to January 2021, according to the PRISMA guidelines.
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Abstract: Purpose: Non-infectious uveitis is a leading cause of vision loss in the developed world. The purpose of this systematic review is to investigate the epidemiology and risk factors of non-infectious uveitis over the last 50 years. Methods: A systematic literature search of Pubmed/MEDLINE database was performed in the 50-year period from January 1971 to January 2021, according to the PRISMA guidelines. Studies that assessed the epidemiology and risk factors for non-infectious uveitis were included. Results: Few epidemiologic studies focus specifically on non-infectious uveitis. In the Unites States, the estimated prevalence of non-infectious uveitis is 121/100,000. The incidence and prevalence varies considerably worldwide. Females and the working age group (20-50 years) appear to be the most affected. Smoking and vitamin D deficiency are the biggest risk factors for non-infectious uveitis, while pregnancy appears to be protective. Additional risk factors include presence of other autoimmune diseases (thyroid disease, diabetes, celiac), pre-eclampsia/eclampsia, psychological stress, and certain medications (bisphosphonates, immune checkpoint inhibitors, female hormone therapy, and etanercept). Discussion: Our systematic review summarizes the incidence and prevalence of non-infectious uveitis and associated modifiable and non-modifiable risk factors.
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Citations
Vaccine-Associated Uveitis after COVID-19 Vaccination
TL;DR: In this paper , the authors evaluated the risk of vaccine-associated uveitis after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and evaluated Uveitis onset interval and clinical presentations in the patients.
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Lower relapses rate with infliximab versus adalimumab in sight threatening uveitis: a multicenter study of 330 patients.
Georgina Maalouf,Anais Andrillon,Mathilde Leclercq,Pascal Sève,Philip Bielefeld,Julie Gueudry,Thomas Sené,Cherif Titah,Thomas Moulinet,Bénédicte Rouvière,Damien Sène,Anne Claire Desbois,Fanny Domont,Sara Touhami,Thomas Thibault,Carolla El Chamieh,Patrice Cacoub,Laurent Kodjikian,Lucie Biard,Bahram Bodaghi,David Saadoun +20 more
TL;DR: In this article , the authors compared the relapse rate of sight-threatening noninfectious uveitis (NIU) in patients treated with infliximab (IFX) or adalimumab (ADA).
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Development and Implementation of the AIDA International Registry for Patients with Non-Infectious Uveitis
Francesca Della Casa,Antonio Vitale,Silvana Guerriero,Jurgen Sota,Rolando Cimaz,Gaafar Ragab,Piero Ruscitti,Rosa Maria Rodrigues Pereira,Francesca Minoia,Emanuela Del Giudice,Giacomo Emmi,Claudia Lomater,Sara Monti,Claudia Canofari,Carla Gaggiano,Giovanni D' Alessio,Elisabetta Miserocchi,Alessandro Conforti,Marilia Ambiel Dagostin,Chiara Mapelli,Maria Pia Paroli,Veronica Parretti,Valeria Albano,Rosa Anna Favale,Luca Marelli,Mohamed I Hegazy,Paola Cipriani,Isabele Parente de Brito Antonelli,Valeria Caggiano,Emma Aragona,A. Laymouna,Gian Marco Tosi,M. Tarsia,Marco Cattalini,Francesco La Torre,Giuseppe Lopalco,Ewa Więsik-Szewczyk,Micol Frassi,Stefano Gentileschi,Heitor F. Giordano,Bruno Frediani,Samuel Katsuyuki Shinjo,Donato Rigante,Petros P. Sfikakis,Alberto Balistreri,Mohamad A. Hussein,Rana Amin,Luca Cantarini,C. Fabiani +48 more
TL;DR: The AIDA registry for patients with non-infectious uveitis (NIU) as mentioned in this paper is a physician-driven, population-and electronic-based registry implemented for both retrospective and prospective collection of real-world demographics, clinical, laboratory, instrumental and socioeconomic data of patients with NIU recruited through the AIDA Network.
Risk of non-infectious uveitis following COVID-19 vaccination in a US claims database
TL;DR: The authors' matched cohort and SCCS analyses using a large claims database did not detect increased NIU risk following COVID-19 vaccination overall in individuals without history of the disease, providing reassurance about the overall safety of vaccination.
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Systematic review of clinical practice guidelines for uveitis
TL;DR: A systematic review of CPGs published on uveitis between 2010 and March 2020 was conducted as mentioned in this paper, which covered screening for, monitoring and treating juvenile idiopathic arthritis (JIA)-associated Uveitis, the use of adalimumab and dexamethasone in treating non-infectious UVEitis, and a top-level summary of assessment, differential diagnosis and referral recommendations for uvethritis, aimed at primary care practitioners.
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References
Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation.
Larissa Shamseer,David Moher,Mike Clarke,Davina Ghersi,Alessandro Liberati,Mark Petticrew,Paul G. Shekelle,Lesley A. Stewart +7 more
TL;DR: The PRISMA-P checklist as mentioned in this paper provides 17 items considered to be essential and minimum components of a systematic review or meta-analysis protocol, as well as a model example from an existing published protocol.
Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop.
TL;DR: In this article, a process of standardizing the methods for reporting clinical data in the field of uveitis has been discussed, and the results used to develop a series of proposals to better standardize the use of these entities.
4.1K
Causes and frequency of blindness in patients with intraocular inflammatory disease.
TL;DR: Cystoid macular oedema is the most frequent complication of uveitis and its occurrence plays a decisive role in the visual outcome of this disease.
890
Incidence and prevalence of uveitis in Northern California: The Northern California Epidemiology of Uveitis Study
TL;DR: In this largest population-based uveitis study in the United States to date, the incidence of uveritis was approximately 3 times that of previous U.S. estimates and increased with the increasing age of patients.
830
Uveitis in Behçet disease: an analysis of 880 patients.
TL;DR: In this paper, the demographic and clinical features, ocular manifestations, complications, visual prognosis, and treatment in a large population of Turkish patients with Behcet uveitis were described.
614