Epicatechin ingested via cocoa products reduces blood pressure in humans: a nonlinear regression model with a Bayesian approach

TL;DR: Investigation of the effects of quercetin after regular intake on blood pressure in overweight-to-obese patients with pre-hypertension and stage I hypertension concluded that supplementation with 162 mg/d quercETin from onion skin extract lowers ABP in patients with hypertension, suggesting a cardioprotective effect of quERCetin.

TL;DR: The safety of these compounds is addressed as well as their potential use in hypertension management and treatment, by addressing the antihypertensive effects of flavonoids.

TL;DR: The habitual intake of flavonoids in Europe is below the amounts found to have a significant health effect, and the distribution of intake was skewed in many countries, especially in Germany.

TL;DR: The current review examines the beneficial effects of flavonoids on both human and animal brain function and attempts to address and link direct and indirect actions of Flavonoids and their derivatives within the central nervous system (CNS).

TL;DR: In conclusion, tea extracts from C. sinensis may have the potential to prevent and protect against cardiovascular disease.

TL;DR: Experimental and clinical studies indicate that polyphenols have the capacity to improve the endothelial control of vascular tone not only in several experimental models of cardiovascular diseases such as hypertension but also in healthy and diseased humans.

TL;DR: It is shown, for the first time to the authors' knowledge, that consumption of cocoa flavanols can significantly affect the growth of select gut microflora in humans, which suggests the potential prebiotic benefits associated with the dietary inclusion of flavanol-rich foods.

TL;DR: The results indicate that the proposed beneficial health effects associated with the consumption of flavanol-containing foods will significantly depend on the stereochemical configuration of the flavanols ingested.