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Enzymes : a practical introduction to structure, mechanism, and data analysis
Robert A. Copeland
- 01 Jan 2000
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TL;DR: This paper presents a meta-analyses of Enzyme Reactions with Multiple Substrates with the aim of determining the mechanism behind Cooperativity in Enzyme Catalysis and its role in enzymology.
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Abstract: A Brief History of Enzymology. Chemical Bonds and Reactions in Biochemistry. Structural Components of Enzymes. Protein-Ligand Binding Equilibria. Kinetics of Single-Substrate Enzyme Reactions. Chemical Mechanisms in Enzyme Catalysis. Experimental Measures of Enzyme Activity. Reversible Inhibitors. Tight Binding Inhibitors. Time-Dependent Inhibition. Enzyme Reactions with Multiple Substrates. Cooperativity in Enzyme Catalysis. Appendices. Index.
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