Journal Article10.1039/C2BM00041E
Enzyme responsive materials: design strategies and future developments
273
TL;DR: This review highlights current and potential future design strategies for ERMs and provides an overview of the present state of the art in the area.
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Abstract: Enzyme responsive materials (ERMs) are a class of stimuli responsive materials with broad application potential in biological settings. This review highlights current and potential future design strategies for ERMs and provides an overview of the present state of the art in the area.
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Citations
•Dissertation
A study of doubly crosslinked microgels and their composites
Zhengxing Cui
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TL;DR: In this paper, a study of pH-responsive doubly crosslinked microgels (DX MGs) and associated investigations to enhance their performance was presented, where the MG particles are based on poly(EA/MAA/x), where EA is the ethyl acrylate, MAA is the methacrylate acid and x represents the crosslinker.
2
Research progress on reduction cleavage of azo bonds in biological systems
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TL;DR: The mechanism and properties of reductants that include glutathione, sodium dithionite and azoreductase, and the reductive cleavage properties of azobenzenes are introduced.
Nano based Drug Delivery System for Cancer Therapy: A Next Generation Theranostics
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Polymeric architecture as a tool for programming sequential enzyme-induced mesophase transitions
16 Nov 2022
TL;DR: In this article , the authors use the reactivities of di-and tri-block amphiphiles towards enzymatic degradation as a tool for programming formulations to undergo three sequential enzymatically induced transitions from micelles to hydrogels and finally to dissolved polymers.
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Acid- and Redox-Responsive Smart Polymeric Nanomaterials for Controlled Drug Delivery
Zeng-Ying Qiao,Yu-Juan Gao +1 more
- 01 Jan 2018
TL;DR: Chemical structure, stimuli-responsive bond, self-assembly property, and drug release behavior of polymeric nanomaterials are focused on, which may offer a guide for optimal design of smart targeted nanodrugs in clinical cancer treatment.
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References
Caspases: Enemies Within
TL;DR: This work has shown that understanding caspase regulation is intimately linked to the ability to rationally manipulate apoptosis for therapeutic gain.
7.2K
Quantum dot bioconjugates for imaging, labelling and sensing
TL;DR: This review looks at current methods for preparing QD bioconjugates as well as presenting an overview of applications, and concludes that the potential of QDs in biology has just begun to be realized and new avenues will arise as the ability to manipulate these materials improves.
6.3K
Matrix metalloproteinases and their inhibitors in connective tissue remodeling.
TL;DR: Latency is overcome by physical, chemical, and enzymatic treatments that separate the cysteine residue from the zinc Expression of the metalloproteinases is switched on by a variety of agents acting through regulatory elements of the gene, particularly the AP‐1 binding site.
3.5K
Matrix Metalloproteinases: A Review
Henning Birkedal-Hansen,William G. I. Moore,M.K. Bodden,L.J. Windsor,B. Birkedal-Hansen,Arthur A. Decarlo,Jeffrey A. Engler +6 more
TL;DR: The present review discusses in detail the primary structures and the overlapping yet distinct substrate specificities of MMPs as well as the mode of activation of the unique MMP precursors.
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Thermo- and pH-responsive polymers in drug delivery.
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