Journal Article10.1039/C0GC00595A
Enzyme-mediated oxidations for the chemist
421
TL;DR: The present state of the art in the use of enzymes and microorganisms for catalytic oxidation and oxyfunctionalization chemistry is reviewed.
read more
About: This article is published in Green Chemistry. The article was published on 08 Feb 2011. The article focuses on the topics: Green chemistry & Catalytic oxidation.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
One-Pot Enzyme Cascade for Controlled Synthesis of Furancarboxylic Acids from 5-Hydroxymethylfurfural by H2O2 Internal Recycling
TL;DR: The byproduct of GOase-catalyzed oxidation of HMF to 2,5-diformylfuran (DFF) was used for horseradish peroxidase (HRP)-mediated regeneration of the oxidized nicotinamide cofactors for subsequent oxidation of DFF promoted by an ADH, thus implementing H 2 O 2 internal recycling.
51
Flow Cytometer-Based High-Throughput Screening System for Accelerated Directed Evolution of P450 Monooxygenases
TL;DR: The first whole-cell, high-throughput screening platform for P450 monooxygenases based on flow cytometry is reported, which can likely be applied to directed evolution campaigns of any P450 Monooxygenase that catalyzes the O-dealkylation of BCCE.
50
Enzymatic Oxyfunctionalization Driven by Photosynthetic Water-Splitting in the Cyanobacterium Synechocystis sp. PCC 6803
Stefanie Böhmer,Katharina Köninger,Álvaro Gómez-Baraibar,Samiro Bojarra,Carolin Mügge,Sandy Schmidt,Marc M. Nowaczyk,Robert Kourist +7 more
TL;DR: The successful enzymatic oxygenation shows that cyanobacterial whole-cell biocatalysis is an applicable approach that allows fuelling selective oxyfunctionalisation reactions at the expense of light and water.
50
A biocatalytic redox isomerisation
TL;DR: Coupling of an alcohol dehydrogenase to an enoate reductase has been successfully applied in one pot for the isomerisation of an allylic alcohol to the corresponding ketone.
49
Photobiocatalytic alcohol oxidation using LED light sources
TL;DR: In this paper, the photocatalytic oxidation of NADH using a flavin photocatalyst and a simple blue LED light source is reported, which enables very significant reductions in energy consumption and CO2 emission.
49
References
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
Dae-Kyun Ro,Eric M. Paradise,Mario Ouellet,Karl Fisher,Karyn L. Newman,John M. Ndungu,Ho Kimberly,Eachus Rachel,Timothy S. Ham,James Kirby,Michelle C. Y. Chang,Sydnor T. Withers,Yoichiro Shiba,Richmond Sarpong,Jay D. Keasling +14 more
TL;DR: The engineering of Saccharomyces cerevisiae to produce high titres (up to 100 mg l-1) of artemisinic acid using an engineered mevalonate pathway, amorphadiene synthase, and a novel cytochrome P450 monooxygenase from A. annua that performs a three-step oxidation of amorpha-4,11-diene to art Artemisinic acid.
2.9K
Industrial biocatalysis today and tomorrow
TL;DR: Biocatalytic processes can now be carried out in organic solvents as well as aqueous environments, so that apolar organic compounds aswell as water-soluble compounds can be modified selectively and efficiently with enzymes and bioc atalytically active cells.
2.3K