Journal Article10.1021/ES300267G
Environmental Tobacco Smoke as a Source of Polycyclic Aromatic Hydrocarbons in Settled Household Dust
Eunha Hoh,Richard N. Hunt,Penelope J.E. Quintana,Joy M. Zakarian,Dale A. Chatfield,Beth C. Wittry,Edgar Rodriguez,Georg E. Matt +7 more
120
TL;DR: House dust PAH loadings in the bedroom and living room in the same home were significantly correlated suggesting PAHs are distributed by tobacco smoke throughout a home, and tobacco smoke generated PAHS are a component of thirdhand smoke.
read more
Abstract: Environmental tobacco smoke is a major contributor to indoor air pollution. Dust and surfaces may remain contaminated long after active smoking has ceased (called ‘thirdhand’ smoke). Polycyclic aromatic hydrocarbons (PAHs) are known carcinogenic components of tobacco smoke found in settled house dust (SHD). We investigated whether tobacco smoke is a source of PAHs in SHD. House dust was collected from 132 homes in urban areas of Southern California. Total PAHs were significantly higher in smoker homes than nonsmoker homes (by concentration: 990 ng/g vs 756 ng/g, p = 0.025; by loading: 1650 ng/m2 vs 796 ng/m2, p = 0.012). We also found significant linear correlations between nicotine and total PAH levels in SHD (concentration, R2 = 0.105; loading, R2 = 0.385). Dust collected per square meter (g/m2) was significantly greater in smoker homes and might dilute PAH concentration in SHD inconsistently. Therefore, dust PAH loading (ng PAH/m2) is a better indicator of PAH content in SHD. House dust PAH loadings in...
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Thirdhand Smoke: New Evidence, Challenges, and Future Directions.
Peyton Jacob,Neal L. Benowitz,Hugo Destaillats,Lara A. Gundel,Bo Hang,Manuela Martins-Green,Georg E. Matt,Penelope J.E. Quintana,Jonathan M. Samet,Suzaynn F. Schick,Prue Talbot,Noel J. Aquilina,Melbourne F. Hovell,Jian-Hua Mao,Todd P. Whitehead +14 more
TL;DR: This Perspective describes the distribution and chemical changes that occur as secondhand tobacco smoke is transformed into thirdhand smoke, studies of environmental contamination by THS, human exposure studies, toxicology studies using animal models and in vitro systems, possible approaches for avoiding exposure, remediation of THS contamination, and priorities for further research.
222
Dose-Response Relationships of Polycyclic Aromatic Hydrocarbons Exposure and Oxidative Damage to DNA and Lipid in Coke Oven Workers
Dan Kuang,Wangzhen Zhang,Qifei Deng,Xiao Zhang,Kun Huang,Lei Guan,Die Hu,Tangchun Wu,Huan Guo +8 more
TL;DR: The findings demonstrate that urinary 1-hydroxypyrene is a useful biomarker for evaluating total PAHs exposure and assessing oxidative damage in coke oven workers and indicated that urinary ΣOH-PAHs and plasma BPDE-Alb adducts can result in significant dose-related increases in oxidative damage to DNA and lipids.
200
Formation mechanism of polycyclic aromatic hydrocarbons beyond the second aromatic ring.
TL;DR: The formation mechanism of polycyclic aromatic hydrocarbons with three fused aromatic rings starting from naphthalene has been studied using accurate ab initio G3(MP2,CC)//B3LYP/6-311G** calculations followed by the kinetic analysis of various reaction pathways and computations of relative product yields.
181
Spatiotemporal analysis and human exposure assessment on polycyclic aromatic hydrocarbons in indoor air, settled house dust, and diet: A review
Yuning Ma,Stuart Harrad +1 more
TL;DR: Evaluation of human exposure to ΣPAH via inhalation, dust and diet ingestion, suggests that while intake via diet and inhalation exceeds that via dust ingestion; all three pathways contribute and merit continued assessment.
181
Indoor Air Pollution and Risk of Lung Cancer among Chinese Female Non-Smokers
Lina Mu,Li Liu,Rungui Niu,Baoxing Zhao,Jianping Shi,Yanli Li,Mya Swanson,William L. Scheider,Jia Su,Shen-Chih Chang,Shun-Zhang Yu,Zuo-Feng Zhang +11 more
TL;DR: Indoor air pollution plays an important role in the development of lung cancer among non-smoking Chinese women and housing characteristics related to poor ventilation, including single-story, less window area, no separate kitchen, no ventilator, and rarely having windows open, are associated with lung cancer.
References
Human cell mutagenicity of oxygenated, nitrated and unsubstituted polycyclic aromatic hydrocarbons associated with urban aerosols.
TL;DR: Based on reported concentrations of PAC in ambient aerosols, it is possible that CPP, DB[ae]P,DB[al]P and BPK could account for a greater proportion of the mutagenicity than B[a]P in some aerosols.
812
Thirdhand Tobacco Smoke: Emerging Evidence and Arguments for a Multidisciplinary Research Agenda
Georg E. Matt,Penelope J.E. Quintana,Hugo Destaillats,Lara A. Gundel,Mohamad Sleiman,Brett C. Singer,Peyton Jacob,Neal L. Benowitz,Jonathan P. Winickoff,Virender K. Rehan,Prue Talbot,Suzaynn F. Schick,Jonathan M. Samet,Yinsheng Wang,Bo Hang,Manuela Martins-Green,James F. Pankow,Melbourne F. Hovell +17 more
TL;DR: The existing evidence on thirdhand smoke (THS) provides strong support for pursuing a programmatic research agenda to close gaps in current understanding of the chemistry, exposure, toxicology, and health effects of THS, as well as its behavioral, economic, and sociocultural considerations and consequences.
Beliefs About the Health Effects of “Thirdhand” Smoke and Home Smoking Bans
Jonathan P. Winickoff,Joan Friebely,Susanne E. Tanski,Cheryl Sherrod,Georg E. Matt,Melbourne F. Hovell,Robert McMillen +6 more
TL;DR: This study demonstrates that beliefs about the health effects of thirdhand smoke are independently associated with home smoking bans, andphasizing that third hand smoke harms the health of children may be an important element in encouraging homesmoking bans.
When smokers move out and non-smokers move in: residential thirdhand smoke pollution and exposure
Georg E. Matt,Penelope J.E. Quintana,Joy M. Zakarian,Addie L. Fortmann,Dale A. Chatfield,Eunha Hoh,Anna M Uribe,Melbourne F. Hovell +7 more
TL;DR: It is indicated that THS accumulates in smokers' homes and persists when smokers move out even after homes remain vacant for 2 months and are cleaned and prepared for new residents.
204
Related Papers (5)
[...]
Georg E. Matt,Penelope J.E. Quintana,Hugo Destaillats,Lara A. Gundel,Mohamad Sleiman,Brett C. Singer,Peyton Jacob,Neal L. Benowitz,Jonathan P. Winickoff,Virender K. Rehan,Prue Talbot,Suzaynn F. Schick,Jonathan M. Samet,Yinsheng Wang,Bo Hang,Manuela Martins-Green,James F. Pankow,Melbourne F. Hovell +17 more