Engineering functional hydrogel microparticle interfaces by controlled oxygen-inhibited photopolymerization
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TL;DR: The combination of finely controlled exposure conditions and predictive simulations enables the generation of tailored particles with microengineered interfaces and gradients in crosslinking density, which dictate solute diffusivity and elasticity, augmenting the utility of this approach in engineering multifunctional, size-excluding hydrogel particles for multiplexed biomolecular sensing.
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About: This article is published in Colloids and Surfaces B: Biointerfaces. The article was published on 01 Aug 2019. and is currently open access.
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Citations
Injectable Microfluidic Hydrogel Microspheres for Cell and Drug Delivery
Zhenyu Zhao,Zhenyu Zhao,Zhen Wang,Gen Li,Zhengwei Cai,Jiezhou Wu,Lei Wang,Lianfu Deng,Ming Cai,Wenguo Cui +9 more
TL;DR: This review begins with a discussion of microfluidic hydrogel microspheres and then introduces the preparation equipment, main principles, and related characteristics of the micro Spheres.
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Natural polymers-based light-induced hydrogels: Promising biomaterials for biomedical applications
TL;DR: The recent advances of the design, development, as well as numerous biomedical applications of natural polymers-based light-induced hydrogels, the advantages and disadvantages of light sources (near-infrared (NIR), visible light and ultraviolet (UV)) as wellAs current status and challenges are discussed.
155
In situ forming microporous gelatin methacryloyl hydrogel scaffolds from thermostable microgels for tissue engineering
Nicole Zoratto,Donatella Di Lisa,Joseph de Rutte,Nurus Sakib,Angelo Roncalli Alves e Silva,Ali Tamayol,Dino Di Carlo,Ali Khademhosseini,Amir Sheikhi +8 more
- 01 Sep 2020
TL;DR: This work identifies the optimal crosslinking condition (exposure time ~60 s) that enables the formation of stable annealed microgel scaffolds and increases the thermostability of GelMA microgels while decreasing their scaffold forming (annealing) capability.
45
The Influence of Vanillin Acrylate Derivative on the Phase Separation Temperature of Environmental Photo-Cross-Linked N-isopropylacrylamide Copolymer and Hydrogel Thin Films
TL;DR: In this paper, the fabrication of thermal and pH-responsive photo-cross-linked polymers and hydrogel thin films has been studied, where N-isopropylacrylamide was used as a thermal responsive monomer, while vanillin 2-((dimethylamino)methyl)-4-formyl-6-methoxyphenyl acrylate (DMAMVA) was synthesized based on vanillin 1.
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Photo-tunable hydrogel mechanical heterogeneity informed by predictive transport kinetics model.
TL;DR: A predictive transport and swelling model is presented to model these effects and then is used to compensate for these effects during printing and is validated experimentally by photopatterning spatially distinct hydrogel elastic moduli using a single photo-tunable poly(ethylene glycol) (PEG) pre-polymer solution.
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