Journal Article10.1016/J.TCB.2006.07.003
Emerging roles of pseudokinases.
TL;DR: Evidence that the pseudokinase STRAD controls the function of the tumour suppressor kinase LKB1 is reviewed and that a single amino acid substitution within the pseudokerase domain of the tyrosine kinase JAK2 leads to several malignant myeloproliferative disorders.
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About: This article is published in Trends in Cell Biology. The article was published on 01 Sep 2006.
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Citations
The function of PTK7 during Xenopus neural crest migration
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TL;DR: In this article , the role of PTK7 in Xenopus ectodermal explants was investigated and it was shown that PTK 7 is a component of the fz7-dsh complex, which is necessary for the inner ear hair cell polarity and neural tube closure.
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Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation
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TL;DR: In this paper, the crystal structure of the Pragmin 906-1368 amino acids C-terminus, which encompasses its kinase domain, was presented, revealing a new dimerization mechanism by which a pseudo-kinase can induce protein tyrosine phosphorylation.
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