Elemental diet is an effective treatment for eosinophilic esophagitis in children and adolescents.

TL;DR: The use of CDH26 as a marker for EG, eosinophilic esophagitis, or allergic inflammatory conditions is discussed in this paper, where the authors also relate to the use of anti-CDH26-based therapeutics to treat allergic inflammatory condition.

TL;DR: This chapter focuses on the history of EoE including initial reports of esophageal eosinophilia prior to 1995, the landmark article identifying EoB as a disorder in1995, the growth of EiE in the literature since 1995, and the development of the First International Gastrointestinal EosInophilic Research Symposium (FIGERS) in 2006.

TL;DR: The disease occurs in adults as well as in children, although it is 8 times more frequent in a pediatric population where the peak of the diagnosis arises during the first three years.

TL;DR: The presence of high concentrations of IEE in esophageal biopsies from patients with dysphagia, normal endoscopy, and normal 24-hr esophagal pH monitoring represents a distinctive clinicopathologic syndrome not previously described.

TL;DR: It is concluded that basal cell hyperplasia of the squamous epithelium and location of the papillae close to the epithelial surface are the histological consequences of gastroesophageal reflux.

TL;DR: Pediatric patients in a series with marked esophageal eosinophilia and chronic symptoms of gastroesphageal reflux disease unresponsive to aggressive medical antireflux therapy had both clinical and histologic improvement after oral corticosteroid therapy.

TL;DR: The spectrum of pediatric eosinophilic esophagitis beyond infancy: a clinical series of 30 children shows marked variation in the severity of the disease in children aged four to six months.